G3BP1

Gene Symbol G3BP1
Entrez Gene 10146
Alt Symbol G3BP, HDH-VIII
Species Human
Gene Type protein-coding
Description GTPase activating protein (SH3 domain) binding protein 1
Other Description ATP-dependent DNA helicase VIII|G3BP-1|GAP SH3 domain-binding protein 1|GAP binding protein|Ras-GTPase-activating protein SH3-domain-binding protein|RasGAP-associated endoribonuclease G3BP|ras GTPase-activating protein-binding protein 1
Swissprots Q13283 Q5HYE9
Accessions CAH05301 EAW61659 EAW61660 EAW61661 EAW61662 Q13283 AK091592 AK128316 AK130003 BAC85272 AK222606 BAD96326 AK300098 BAG61899 AK303580 BAH13990 AK309172 AK311635 AK312572 BAG35467 BC006997 AAH06997 BC108278 AAI08279 BG703413 BT019384 AAV38191 BU517281 BX647869 CAI46065 BX648012 CAI46067 CR536535 CAG38772 DQ893058 ABM83984 DQ896308 ABM87307 U32519 AAB07787 X78262 XM_006714749 XP_006714812 XM_006714750 XP_006714813 NM_005754 NP_005745 NM_198395 NP_938405
Function May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium- dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA. {ECO:0000269|PubMed:11604510, ECO:0000269|PubMed:9889278}.
Subcellular Location Cytoplasm. Cytoplasm, cytosol. Cytoplasmic granule. Cell membrane. Nucleus. Note=Cytoplasmic in proliferating cells, can be recruited to the plasma membrane in exponentially growing cells (By similarity). Cytosolic and partially nuclear in resting cells. Recruited to stress granules (SGs) upon either arsenite or high temperature treatment. Recruitment to SGs is influenced by HRAS. {ECO:0000250}.
Tissue Specificity Ubiquitous.

Mouse/Human Phospho-G3BP1 / G3BP (Ser232) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1514 from LifeSpan Bioscience

Category ELISA Kit
Prices $550.00
Sizes 1 plate

Mouse/Human G3BP1 / G3BP ELISA Kit (Cell-Based ELISA) - LS-F2004 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate

Rabbit anti-G3BP1 Antibody, Affinity Purified - PLA0231 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunofluorescence</B>: This antibody is qualified for the Proximity Ligation Assay (PLA). The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red).

G3BP1 (Human) IP-WB Antibody Pair - H00010146-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

G3BP-1 Colorimetric Cell-Based ELISA Kit - CB5280 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

G3BP-1 (Phospho-Ser232) Colorimetric Cell-Based ELISA Kit - CBP1560 from Assay Biotechnology

Category ELISA Kit
Prices $480.00, $960.00, $1,440.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

GTPase activating protein (SH3 domain) binding protein 1, ELISA Kit - MBS9338691 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0ng/ml.
Range 3.12ng/ml-100ng/ml.

G3BP-1 ELISA Kit - DEIA-XYA706 from Creative Diagnostics

Category ELISA Kit

G3BP-1 (Phospho-Ser232) ELISA Kit - DEIA-XYA707 from Creative Diagnostics

Category ELISA Kit

Human G3BP1 ELISA Kit - E083788 from Biobool

Category ELISA Kit

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9358665 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9349261 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9347148 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9344754 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9346319 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9368872 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9369485 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9351314 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9350484 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9350179 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9358168 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9356346 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9363684 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9368723 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras GTPase-Activating Protein-Binding Protein 1 (G3BP1), ELISA Kit - MBS9355760 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Search more