Gene Symbol | ALCAM |
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Entrez Gene | 214 |
Alt Symbol | CD166, MEMD |
Species | Human |
Gene Type | protein-coding |
Description | activated leukocyte cell adhesion molecule |
Other Description | CD166 antigen |
Swissprots | Q1HGM9 B2RNS3 B4DTU0 Q1HGM8 Q13740 Q6PEY4 Q6ZS95 O60892 |
Accessions | EAW79755 EAW79756 EAW79757 Q13740 AB074167 AK054632 BAG51401 AK095833 AK127617 BAC87059 AK300362 BAG62102 AK301804 BAG63255 AK316113 BAH14484 AL833702 AY644765 AAV28819 BC029639 BC041127 BC057809 AAH57809 BC137096 AAI37097 BC137097 AAI37098 CA430528 CB145726 DA318514 DB541501 DQ486139 ABF48405 DQ486140 ABF48406 L38608 AAB59499 Y10183 CAA71256 NM_001243280 NP_001230209 NM_001243281 NP_001230210 NM_001243283 NP_001230212 NM_001627 NP_001618 |
Function | Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines. {ECO:0000269|PubMed:9502422}. |
Top Pathways | Cell adhesion molecules (CAMs) |
ALCAM Human ELISA Kit - ab113317 from Abcam
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Human ALCAM / CD166 ELISA Kit (Sandwich ELISA) - LS-F2818 from LifeSpan Bioscience
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Human ALCAM / CD166 ELISA Kit (Sandwich ELISA) - LS-F3948 from LifeSpan Bioscience
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Human ALCAM / CD166 ELISA Kit (Sandwich ELISA) - LS-F29 from LifeSpan Bioscience
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Mouse ALCAM / CD166 ELISA Kit (Sandwich ELISA) - LS-F11073 from LifeSpan Bioscience
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Human ALCAM / CD166 ELISA Kit (Sandwich ELISA) - LS-F11072 from LifeSpan Bioscience
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Human ALCAM ELISA Kit - RAB0013 from Sigma-Aldrich
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Human ALCAM DuoSet ELISA - DY656 from R&D Systems
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Mouse ALCAM DuoSet ELISA - DY1172 from R&D Systems
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Human ALCAM ELISA kit - 55R-2106 from Fitzgerald
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Human ALCAM ELISA Kit - abx054712 from Abbexa
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Human ALCAM ELISA Kit - abx150606 from Abbexa
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Human CD166 ELISA Kit - abx056071 from Abbexa
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Activated Leukocyte Cell Adhesion Molecule, ALCAM, Human, ELISA Kit - CSB-E04487h from ARP American Research Products
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Activated Leukocyte Cell Adhesion Molecule, Human, ELISA Kit - E01A0319 from ARP American Research Products
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Activated Leukocyte Cell Adhesion Molecule, ALCAM, Human, ELISA Kit - E-EL-H0305 from ARP American Research Products
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CD166 antigen, ALCAM, Human, ELISA Kit - E0002h from ARP American Research Products
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Activated Leukocyte Cell Adhesion Molecule, ALCAM, Rabbit, ELISA Kit - E-EL-RB0900 from ARP American Research Products
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Activated Leukocyte Cell Adhesion Molecule, ALCAM, Chicken, ELISA Kit - E-EL-Ch0072 from ARP American Research Products
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Activated Leukocyte Cell Adhesion Molecule, ALCAM, Porcine, ELISA Kit - E-EL-P1789 from ARP American Research Products
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Activated Leukocyte Cell Adhesion Molecule, ALCAM, Monkey, ELISA Kit - E-EL-MK0816 from ARP American Research Products
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ALCAM (Human) ELISA Kit - KA1692 from Acris Antibodies
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Human ALCAM ELISA - ELH-ALCAM from RayBiotech
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Human ALCAM ELISA Kit - HA0326 from NeoScientific
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Anserine ALCAM ELISA Kit - AA0326 from NeoScientific
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