ALCAM

Gene Symbol ALCAM
Entrez Gene 214
Alt Symbol CD166, MEMD
Species Human
Gene Type protein-coding
Description activated leukocyte cell adhesion molecule
Other Description CD166 antigen
Swissprots Q1HGM9 B2RNS3 B4DTU0 Q1HGM8 Q13740 Q6PEY4 Q6ZS95 O60892
Accessions EAW79755 EAW79756 EAW79757 Q13740 AB074167 AK054632 BAG51401 AK095833 AK127617 BAC87059 AK300362 BAG62102 AK301804 BAG63255 AK316113 BAH14484 AL833702 AY644765 AAV28819 BC029639 BC041127 BC057809 AAH57809 BC137096 AAI37097 BC137097 AAI37098 CA430528 CB145726 DA318514 DB541501 DQ486139 ABF48405 DQ486140 ABF48406 L38608 AAB59499 Y10183 CAA71256 NM_001243280 NP_001230209 NM_001243281 NP_001230210 NM_001243283 NP_001230212 NM_001627 NP_001618
Function Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines. {ECO:0000269|PubMed:9502422}.
Top Pathways Cell adhesion molecules (CAMs)

ALCAM CRISPR/Cas9 KO Plasmid (h) - sc-418418 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALCAM HDR Plasmid (h) - sc-418418-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALCAM Double Nickase Plasmid (h) - sc-418418-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALCAM Double Nickase Plasmid (h2) - sc-418418-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALCAM CRISPR Activation Plasmid (h) - sc-418418-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALCAM CRISPR Activation Plasmid (h2) - sc-418418-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALCAM Lentiviral Activation Particles (h) - sc-418418-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALCAM Lentiviral Activation Particles (h2) - sc-418418-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALCAM siRNA (h) - sc-43023 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALCAM shRNA Plasmid (h) - sc-43023-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALCAM shRNA (h) Lentiviral Particles - sc-43023-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALCAM/CD166 RNAi - H00000214-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU143881 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3042 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3042 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12929 from Sigma-Aldrich

Category miRNA

ALCAM siRNA (Human) - CRH0149 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ALCAM - MBS8205581 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ALCAM (NM_001627.3) - SHH234754 from Creative biogene

Category siRNA
Species Reactivities Human

ALCAM shRNA Plasmid (Human) - CHH0149 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ALCAM miRNA 3'UTR clone - MiUTR4H-TG00260 from Creative biogene

Species Reactivities Human
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