| Gene Symbol |
SYP
|
| Entrez Gene |
6855
|
| Alt Symbol |
MRX96, MRXSYP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
synaptophysin
|
| Other Description |
major synaptic vesicle protein P38
|
| Swissprots |
P08247 B2R7L6 B7Z359 Q6P2F7
|
| Accessions |
AAB92358 EAW50684 EAW50685 P08247 AK094376 AK295524 BAH12095 AK313030 BAG35863 AK315953 BAH14324 BC032385 BC064550 AAH64550 BQ637168 HQ448085 ADQ32566 X06389 CAA29686 XM_011543950 XP_011542252 XM_011543951 XP_011542253 NM_003179 NP_003170
|
| Function |
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.
|
| Tissue Specificity |
Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
|
![Western Blot: Synaptophysin Overexpression Lysate (Adult Normal) [NBL1-16644] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Synaptophysin.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6162_Synaptophysin%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16644-img0002.jpg)