Gene Symbol | SYP |
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Entrez Gene | 6855 |
Alt Symbol | MRX96, MRXSYP |
Species | Human |
Gene Type | protein-coding |
Description | synaptophysin |
Other Description | major synaptic vesicle protein P38 |
Swissprots | P08247 B2R7L6 B7Z359 Q6P2F7 |
Accessions | AAB92358 EAW50684 EAW50685 P08247 AK094376 AK295524 BAH12095 AK313030 BAG35863 AK315953 BAH14324 BC032385 BC064550 AAH64550 BQ637168 HQ448085 ADQ32566 X06389 CAA29686 XM_011543950 XP_011542252 XM_011543951 XP_011542253 NM_003179 NP_003170 |
Function | Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome. |
Tissue Specificity | Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype. |
SYP CRISPR/Cas9 KO Plasmid (h) - sc-400487 from Santa Cruz Biotechnology
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SYP HDR Plasmid (h) - sc-400487-HDR from Santa Cruz Biotechnology
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SYP Double Nickase Plasmid (h) - sc-400487-NIC from Santa Cruz Biotechnology
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SYP Double Nickase Plasmid (h2) - sc-400487-NIC-2 from Santa Cruz Biotechnology
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SYP CRISPR Activation Plasmid (h) - sc-400487-ACT from Santa Cruz Biotechnology
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SYP CRISPR Activation Plasmid (h2) - sc-400487-ACT-2 from Santa Cruz Biotechnology
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SYP Lentiviral Activation Particles (h) - sc-400487-LAC from Santa Cruz Biotechnology
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SYP Lentiviral Activation Particles (h2) - sc-400487-LAC-2 from Santa Cruz Biotechnology
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SYP siRNA (h) - sc-36597 from Santa Cruz Biotechnology
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SYP shRNA Plasmid (h) - sc-36597-SH from Santa Cruz Biotechnology
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SYP shRNA (h) Lentiviral Particles - sc-36597-V from Santa Cruz Biotechnology
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Synaptophysin RNAi - H00006855-R01 from Novus Biologicals
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MISSION® esiRNA - EHU053371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20907 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20907 from Sigma-Aldrich
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SYP siRNA (Human) - CRH4687 from Cohesion Biosciences
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SYP - MBS8214647 from MyBioSource
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shRNA set against Human SYP (NM_003179.2) - SHH421864 from Creative biogene
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shRNA set against Human SYP(NM_003179.2) - SHL050796 from Creative biogene
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Human SYP siRNA - orb265189 from Biorbyt
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SYP shRNA Plasmid (Human) - CHH4687 from Cohesion Biosciences
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SYP miRNA 3'UTR clone - MiUTR1H-10119 from Creative biogene
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