Gene Symbol | SYP |
---|---|
Entrez Gene | 6855 |
Alt Symbol | MRX96, MRXSYP |
Species | Human |
Gene Type | protein-coding |
Description | synaptophysin |
Other Description | major synaptic vesicle protein P38 |
Swissprots | P08247 B2R7L6 B7Z359 Q6P2F7 |
Accessions | AAB92358 EAW50684 EAW50685 P08247 AK094376 AK295524 BAH12095 AK313030 BAG35863 AK315953 BAH14324 BC032385 BC064550 AAH64550 BQ637168 HQ448085 ADQ32566 X06389 CAA29686 XM_011543950 XP_011542252 XM_011543951 XP_011542253 NM_003179 NP_003170 |
Function | Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome. |
Tissue Specificity | Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype. |