SYP

Gene Symbol SYP
Entrez Gene 6855
Alt Symbol MRX96, MRXSYP
Species Human
Gene Type protein-coding
Description synaptophysin
Other Description major synaptic vesicle protein P38
Swissprots P08247 B2R7L6 B7Z359 Q6P2F7
Accessions AAB92358 EAW50684 EAW50685 P08247 AK094376 AK295524 BAH12095 AK313030 BAG35863 AK315953 BAH14324 BC032385 BC064550 AAH64550 BQ637168 HQ448085 ADQ32566 X06389 CAA29686 XM_011543950 XP_011542252 XM_011543951 XP_011542253 NM_003179 NP_003170
Function Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.
Tissue Specificity Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.

Synaptophysin (D35E4) Rabbit mAb - 5461 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D35E4
Western blot analysis of extracts from mouse and rat brain using Synaptophysin (D35E4) Rabbit mAb.

Synaptophysin (D40C4) Rabbit mAb - 5467 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D40C4
Western blot analysis of extracts from mouse and rat brain using Synaptophysin (D40C4) Rabbit mAb.

Synaptophysin (7H12) Mouse mAb (IF Formulated) - 9020 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone 7H12
Confocal immunofluorescent analysis of mouse brain (left) and mouse retina (right) using Synaptophysin (7H12) Mouse mAb (IF Formulated) (green) and CNPase (D83E10) XP ® Rabbit mAb (Alexa Fluor ® 555 Conjugate) #5715 (red, left). Blue pseudocolor = DRAQ5 ® #4084 (fluorescent DNA dye).

Synaptophysin (7H12) Mouse mAb - 12270 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 7H12
Western blot analysis of extracts from various tissues and cell lines using Synaptophysin (7H12) Mouse mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

Synaptophysin Antibody - 4329 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from rat brain, mouse brain and human cerebellum using Synaptophysin Antibody.

SYP (A-9) - sc-365488 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SYP (A-9): sc-365488. Western blot analysis of SYP expression in PC-12 (A) and IMR-32 (B) whole cell lysates.

SYP (4H255) - sc-58301 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SYP (4H255): sc-58301. Western blot analysis of SYP expression in IMR-32 (A) and BE (2)-M17 (B) whole cell lysates and rat brain (C) and mouse brain (D) tissue extracts.

SYP (C-12) - sc-365447 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SYP (C-12): sc-365447. Western blot analysis of SYP expression in IMR-32 whole cell lysate.

SYP (C-20) - sc-7568 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SYP (C-20): sc-7568. Western blot analysis of SYP expression in mouse (A) and rat (B) brain extracts and PC-12 (C) whole cell lysate.

SYP (D-4) - sc-17750 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SYP (D-4): sc-17750. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human brain tumor showing membrane staining.

SYP (H-8) - sc-55507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SYP (H-8): sc-55507. Western blot analysis of SYP expression in IMR-32 whole cell lysate (A) and rat (B) and mouse (C) brain tissue extracts.

SYP (H-93) - sc-9116 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SYP (H-93): sc-9116. Immunofluorescence staining of methanol-fixed PC-12 cells showing membrane staining.

SYP (N-19) - sc-7569 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SYP (N-19): sc-7569. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing weak nuclear staining of exocrine glandular cells and strong cytoplasmic staining of Islets of Langerhans.

SYP (SVP38) - sc-12737 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SYP (SVP38): sc-12737. Western blot analysis of SYP expression in mouse (A) and rat (B) brain extracts and PC-12 (C) whole cell lysate.

SYP (2) - sc-136271 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
SYP (2): sc-136271. Immunofluorescence staining of PC-12 cells showing cytoplasmic localization.

p-SYP (Tyr 81) - sc-130606 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Synaptophysin antibody - ab53166 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Synaptophysin antibody (ab53166) at 1/500 dilutionLane 1 : LOVO cell extractLane 2 : LOVO cell extract with immunising peptide

Anti-Synaptophysin antibody - ab7837 from Abcam

Prices $378.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab7837 stained PC12 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab7837, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Synaptophysin antibody [7H12] - ab96487 from Abcam

Host Mouse
Clonality Monoclonal
Clone 7H12
Anti-Synaptophysin antibody [7H12] (ab96487) at 1/500 dilution + Rat brain tissue lysate

Anti-Synaptophysin antibody [EP10] - ab69539 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone EP10
All lanes : Anti-Synaptophysin antibody [EP10] (ab69539) at 1 µg/mlLane 1 : Molecular weight markerLane 2 : Human brain extractdeveloped using the ECL technique

Anti-Synaptophysin antibody [EP1098Y] - ab52636 from Abcam

Prices $403.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1098Y
Anti-Synaptophysin antibody [EP1098Y] (ab52636) at 1/200000 dilution + Rat brain membraneSecondaryGoat anti-rabbit HRP labeled at 1/2000 dilution

Anti-Synaptophysin antibody [EPR1097-2] - ab178412 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1097-2
Immunofluorescent analysis of PC12 cells labeling Synaptophysin with ab178412 at 1/50 (green) and DAPI staining (blue).

Anti-Synaptophysin antibody, prediluted - ab75303 from Abcam

Prices $376.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
ab75303 at staining Synaptophysin in human GI tumor by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.

Anti-Synaptophysin antibody, prediluted - ab8547 from Abcam

Prices $370.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal

Anti-Synaptophysin antibody, prediluted - ab82745 from Abcam

Prices $370.00
Sizes 6 ml
Host Rabbit
Clonality Polyclonal
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