Gene Symbol | ARFGAP3 |
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Entrez Gene | 26286 |
Alt Symbol | ARFGAP1 |
Species | Human |
Gene Type | protein-coding |
Description | ADP-ribosylation factor GTPase activating protein 3 |
Other Description | ADP-ribosylation factor GTPase activating protein 1|ADP-ribosylation factor GTPase-activating protein 3|ARF GAP 3 |
Swissprots | Q9NT10 Q9BSC6 Q9H9J0 Q9Y4V3 Q9NP61 Q9NUP5 E9PB03 Q9Y4V4 |
Accessions | EAW73275 EAW73276 Q9NP61 AF111847 AAF40310 AK002083 BAA92076 AK022768 BAB14236 AK127525 AK297635 BAH12636 AK300531 BAH13298 AK307967 AK315720 AL137598 CAB70834 AL159143 CAB76901 BC005122 AAH05122 BC041383 BI547713 BQ019944 CA431867 CR456382 CAG30268 CU012940 CAK54371 CU013228 CAK54670 DB458974 DQ893007 ABM83933 DQ896253 ABM87252 XM_005261525 XP_005261582 NM_001142293 NP_001135765 NM_014570 NP_055385 |
Function | GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. {ECO:0000269|PubMed:11172815}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17760859}. Golgi apparatus membrane {ECO:0000269|PubMed:17760859}; Peripheral membrane protein {ECO:0000269|PubMed:17760859}; Cytoplasmic side {ECO:0000269|PubMed:17760859}. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment. |
Tissue Specificity | Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary. {ECO:0000269|PubMed:10704287}. |
Top Pathways | Endocytosis |
ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), Human, ELISA Kit - E01A1010 from ARP American Research Products
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7213350 from MyBioSource
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7235368 from MyBioSource
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7251004 from MyBioSource
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7245430 from MyBioSource
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7221380 from MyBioSource
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7253688 from MyBioSource
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7229113 from MyBioSource
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7248830 from MyBioSource
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7201991 from MyBioSource
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7243978 from MyBioSource
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ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit - MBS7216117 from MyBioSource
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ADP ribosylation factor GTPase activating protein 3 (ARFGAP3), ELISA Kit - MBS7240784 from MyBioSource
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Human ARFGAP3 ELISA Kit - E000969 from Biobool
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anti-ARFGAP3 antibody - ARG55517 from Arigo Biolaboratories
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anti-ARFGAP3 antibody - ARG63139 from Arigo Biolaboratories
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