ARFGAP3

Gene Symbol ARFGAP3
Entrez Gene 26286
Alt Symbol ARFGAP1
Species Human
Gene Type protein-coding
Description ADP-ribosylation factor GTPase activating protein 3
Other Description ADP-ribosylation factor GTPase activating protein 1|ADP-ribosylation factor GTPase-activating protein 3|ARF GAP 3
Swissprots Q9NT10 Q9BSC6 Q9H9J0 Q9Y4V3 Q9NP61 Q9NUP5 E9PB03 Q9Y4V4
Accessions EAW73275 EAW73276 Q9NP61 AF111847 AAF40310 AK002083 BAA92076 AK022768 BAB14236 AK127525 AK297635 BAH12636 AK300531 BAH13298 AK307967 AK315720 AL137598 CAB70834 AL159143 CAB76901 BC005122 AAH05122 BC041383 BI547713 BQ019944 CA431867 CR456382 CAG30268 CU012940 CAK54371 CU013228 CAK54670 DB458974 DQ893007 ABM83933 DQ896253 ABM87252 XM_005261525 XP_005261582 NM_001142293 NP_001135765 NM_014570 NP_055385
Function GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. {ECO:0000269|PubMed:11172815}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17760859}. Golgi apparatus membrane {ECO:0000269|PubMed:17760859}; Peripheral membrane protein {ECO:0000269|PubMed:17760859}; Cytoplasmic side {ECO:0000269|PubMed:17760859}. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
Tissue Specificity Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary. {ECO:0000269|PubMed:10704287}.
Top Pathways Endocytosis

ARFGAP1/3 CRISPR/Cas9 KO Plasmid (h) - sc-406509 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARFGAP1/3 HDR Plasmid (h) - sc-406509-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARFGAP1/3 Double Nickase Plasmid (h) - sc-406509-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARFGAP1/3 Double Nickase Plasmid (h2) - sc-406509-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARFGAP1/3 CRISPR Activation Plasmid (h) - sc-406509-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARFGAP1/3 CRISPR Activation Plasmid (h2) - sc-406509-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARFGAP1/3 Lentiviral Activation Particles (h) - sc-406509-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARFGAP1/3 Lentiviral Activation Particles (h2) - sc-406509-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARFGAP1/3 siRNA (h) - sc-60200 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ARFGAP1/3 shRNA Plasmid (h) - sc-60200-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ARFGAP1/3 shRNA (h) Lentiviral Particles - sc-60200-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ARFGAP3 RNAi - H00026286-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU144381 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3394 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3394 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07650 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07650

ARFGAP3 siRNA (Human) - CRH8806 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ARFGAP3 - MBS8229149 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ARFGAP3 (NM_014570.4) - SHH239170 from Creative biogene

Category siRNA
Species Reactivities Human

ARFGAP3 shRNA Plasmid (Human) - CHH8806 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ARFGAP3 miRNA 3'UTR clone - MiUTR3H-12447 from Creative biogene

Species Reactivities Human

ARFGAP3 miRNA 3'UTR clone - MiUTR3H-12448 from Creative biogene

Species Reactivities Human
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