ARFGAP3

Gene Symbol ARFGAP3
Entrez Gene 26286
Alt Symbol ARFGAP1
Species Human
Gene Type protein-coding
Description ADP-ribosylation factor GTPase activating protein 3
Other Description ADP-ribosylation factor GTPase activating protein 1|ADP-ribosylation factor GTPase-activating protein 3|ARF GAP 3
Swissprots Q9NT10 Q9BSC6 Q9H9J0 Q9Y4V3 Q9NP61 Q9NUP5 E9PB03 Q9Y4V4
Accessions EAW73275 EAW73276 Q9NP61 AF111847 AAF40310 AK002083 BAA92076 AK022768 BAB14236 AK127525 AK297635 BAH12636 AK300531 BAH13298 AK307967 AK315720 AL137598 CAB70834 AL159143 CAB76901 BC005122 AAH05122 BC041383 BI547713 BQ019944 CA431867 CR456382 CAG30268 CU012940 CAK54371 CU013228 CAK54670 DB458974 DQ893007 ABM83933 DQ896253 ABM87252 XM_005261525 XP_005261582 NM_001142293 NP_001135765 NM_014570 NP_055385
Function GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. {ECO:0000269|PubMed:11172815}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17760859}. Golgi apparatus membrane {ECO:0000269|PubMed:17760859}; Peripheral membrane protein {ECO:0000269|PubMed:17760859}; Cytoplasmic side {ECO:0000269|PubMed:17760859}. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
Tissue Specificity Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary. {ECO:0000269|PubMed:10704287}.
Top Pathways Endocytosis

ARFGAP3 293 Cell Lysate - 407161 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

ARFGAP3 Overexpression Lysate (Native) - NBL1-07657 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ARFGAP3 Overexpression Lysate (Adult Normal) [NBL1-07657] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ARFGAP3.

ARFGAP1/3 (h4): 293T Lysate - sc-174378 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

ARFGAP3 Over-expression Lysate Product - GWB-73F430 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human ARFGAP3 Knockdown Stable Cell Line - CSC-DC000836 from Creative biogene

Category Cell Line
Species Human
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