TNPO1

Gene Symbol	TNPO1
Entrez Gene	3842
Alt Symbol	IPO2, KPNB2, MIP, MIP1, TRN
Species	Human
Gene Type	protein-coding
Description	transportin 1
Other Description	M9 region interaction protein|importin 2|importin beta 2|importin beta-2|karyopherin (importin) beta 2|karyopherin beta-2|transportin-1
Swissprots	B4DVC6 Q92975 Q92973 Q92957
Accessions	EAW95713 EAW95714 EAW95715 Q92973 AK055669 AK124768 AK299671 BAG61582 AK301021 BAG62638 AK308177 BC040340 AAH40340 EU176628 ABW03429 U70322 AAC50723 U72069 AAB58254 U72395 AAB68948 XM_005248500 XP_005248557 XM_005248501 XP_005248558 XR_948249 NM_002270 NP_002261 NM_153188 NP_694858
Function	Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Involved in nuclear import of M9- containing proteins. In vitro, binds directly to the M9 region of the heterogeneous nuclear ribonucleoproteins (hnRNP), A1 and A2 and mediates their nuclear import. Appears also to be involv
Subcellular Location	Cytoplasm. Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Transportin 1 protein fragment - ab114514 from Abcam Category Protein Source Wheat germ Species Human

Transportin 1 peptide - ab86629 from Abcam Category Peptide

TNPO1 / Transportin 1 Antibody Blocking Peptide - LS-E6575 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Transportin 1 Protein - H00003842-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TNPO1-Antibody-N-term-Blocking-Peptide - BP1934e from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human Transportin 1 Protein - abx069451 from Abbexa Category Protein Source E.coli Species Human

Transportin-1 (TNPO1) - H00003842-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Transportin-1 (TNPO1) - H00003842-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Transportin 1 (TNPO1), Human - 20-6513 from ARP American Research Products Category Protein Prices $495.00 Sizes 50 µg Source E.coli Species Human

Recombinant Human TNPO1 - TNPO1-31605TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Transportin 1 (TNPO1) - RPA272Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Transportin 1 (TNPO1) - RPA272Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Transportin 1 (TNPO1) - RPA272Bo01 from Uscn Life Science Inc. Category Protein Source E.coli Species Bovine

Recombinant Transportin 1 (TNPO1) - RPA272Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Transportin-1(TNPO1) ,partial - CSB-YP835716HU CSB-EP835716HU CSB-BP835716HU CSB-MP835716HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MIP1 protein - 80R-4323 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source Insect cells

Transportin 1 (TNPO1) - RPU144154 from Biomatik Category Protein Prices $234.30, $468.60, $702.90 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

Importin-beta-2-TNPO1-Antibody-C-term-Blocking-peptide - BP1934b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNPO1-Antibody-C-term-Blocking-Peptide - BP1934d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Importin-beta-2-TNPO1-Antibody-N-term-Blocking-peptide - BP1934a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNPO1 Peptide, Human - M34GP16405H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Transportin 1 (TNPO1) - RPU44154 from Biomatik Category Protein Prices $187.00, $383.00, $586.00, $698.64 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

TNPO1 Recombinant Protein (OPCD07621) - OPCD07621 from Aviva Systems Biology Category Protein Source E.coli Species Human

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