TNPO1

Gene Symbol	TNPO1
Entrez Gene	3842
Alt Symbol	IPO2, KPNB2, MIP, MIP1, TRN
Species	Human
Gene Type	protein-coding
Description	transportin 1
Other Description	M9 region interaction protein|importin 2|importin beta 2|importin beta-2|karyopherin (importin) beta 2|karyopherin beta-2|transportin-1
Swissprots	B4DVC6 Q92975 Q92973 Q92957
Accessions	EAW95713 EAW95714 EAW95715 Q92973 AK055669 AK124768 AK299671 BAG61582 AK301021 BAG62638 AK308177 BC040340 AAH40340 EU176628 ABW03429 U70322 AAC50723 U72069 AAB58254 U72395 AAB68948 XM_005248500 XP_005248557 XM_005248501 XP_005248558 XR_948249 NM_002270 NP_002261 NM_153188 NP_694858
Function	Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Involved in nuclear import of M9- containing proteins. In vitro, binds directly to the M9 region of the heterogeneous nuclear ribonucleoproteins (hnRNP), A1 and A2 and mediates their nuclear import. Appears also to be involv
Subcellular Location	Cytoplasm. Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

karyopherin β2 (D45) - sc-32314 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

karyopherin β2 (H-300) - sc-11368 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

karyopherin β2 (L5E3) - sc-101539 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rat Clonality Monoclonal

karyopherin β2 (F-6) - sc-166127 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

karyopherin β2/2B (C-20) - sc-6913 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

karyopherin β2/2B (N-19) - sc-6914 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-Transportin 1 antibody - ab67352 from Abcam Prices $376.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Transportin 1 antibody [D45] - ab10303 from Abcam Prices $403.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone D45

Anti-Transportin 1 antibody - N-terminal - ab191539 from Abcam Prices $384.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody - LS-C89673 from LifeSpan Bioscience Prices $485.00 Sizes 50 µl Host Mouse Clonality Monoclonal

Anti-TNPO1 / Transportin 1 Antibody (clone 3G2) - LS-C197584 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3G2

Anti-TNPO1 / Transportin 1 Antibody (aa45-75, AP) - LS-C271928 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (aa45-75, APC) - LS-C271929 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (aa45-75, Biotin) - LS-C271930 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (aa45-75, FITC) - LS-C271931 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (aa45-75, Azide-free, HRP) - LS-C271932 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (aa45-75, PE) - LS-C271934 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (clone D45) - LS-C82235 from LifeSpan Bioscience Prices $450.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone D45

Anti-TNPO1 / Transportin 1 Antibody (clone D45) - LS-C82277 from LifeSpan Bioscience Prices $380.00 Sizes 50 µl Host Mouse Clonality Monoclonal Clone D45

Anti-TNPO1 / Transportin 1 Antibody (aa593-836, Biotin) - LS-C298004 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (aa597-837, Biotin) - LS-C298007 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (aa626-836, Biotin) - LS-C298005 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (aa593-836, FITC) - LS-C301687 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (aa597-837, FITC) - LS-C301689 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TNPO1 / Transportin 1 Antibody (aa626-836, FITC) - LS-C301688 from LifeSpan Bioscience Prices $425.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Search more