PARD6B

Gene Symbol	PARD6B
Entrez Gene	84612
Alt Symbol	PAR6B
Species	Human
Gene Type	protein-coding
Description	par-6 family cell polarity regulator beta
Other Description	PAR-6 beta|par-6 partitioning defective 6 homolog beta|partitioning defective 6 homolog beta
Swissprots	Q9BYG5 Q9Y510 A2A2A7
Accessions	EAW75615 EAW75616 EAW75617 Q9BYG5 AB044555 BAB40756 AB178534 BAF92013 BC060847 AAH60847 CA435324 HQ448524 ADQ33003 NM_032521 NP_115910
Function	Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Subcellular Location	Cytoplasm. Cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}.
Tissue Specificity	Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
Top Pathways	Tight junction, Endocytosis, Hippo signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-PARD6B-cDNA-Clone - DC08212 from Abgent, a WuXi AppTec company Prices $502.20 Sizes 10 µg Species Human Accession BC060847

PARD6B - MBS1276564 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC060847

Human PARD6B Gene ORF cDNA clone in cloning vector - HG15988-G from Sino Biological Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid, N-His tag - HG15988-NH from Sino Biological Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid, C-His tag - HG15988-CH from Sino Biological Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15988-NF from Sino Biological Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid - HG15988-UT from Sino Biological Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15988-CF from Sino Biological Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15988-NM from Sino Biological Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15988-CM from Sino Biological Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid, C-HA tag - HG15988-CY from Sino Biological Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid, N-HA tag - HG15988-NY from Sino Biological Species Human

Human PARD6B ORF Clone (BC060847) - CDCS416302 from Creative biogene Species Human Accession Q9BYG5

Human PARD6B ORF clone (BC060847) - CDCB157593 from Creative biogene Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15988-ACG from Sino Biological Species Human

Human PARD6B Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15988-ACR from Sino Biological Species Human

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