PARD6B

Gene Symbol PARD6B
Entrez Gene 84612
Alt Symbol PAR6B
Species Human
Gene Type protein-coding
Description par-6 family cell polarity regulator beta
Other Description PAR-6 beta|par-6 partitioning defective 6 homolog beta|partitioning defective 6 homolog beta
Swissprots Q9BYG5 Q9Y510 A2A2A7
Accessions EAW75615 EAW75616 EAW75617 Q9BYG5 AB044555 BAB40756 AB178534 BAF92013 BC060847 AAH60847 CA435324 HQ448524 ADQ33003 NM_032521 NP_115910
Function Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Subcellular Location Cytoplasm. Cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}.
Tissue Specificity Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
Top Pathways Tight junction, Endocytosis, Hippo signaling pathway, Rap1 signaling pathway

PARD6B (E-6) - sc-390452 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PARD6B (E-6): sc-390452. Western blot analysis of PARD6B expression in HeLa (A) and Caki-1 (B) whole cell lysates.

PARD6B (F-5) - sc-390937 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PARD6B (F-5): sc-390937. Western blot analysis of PARD6B expression in HeLa (A) and Caki-1 (B) whole cell lysates.

PARD6B (H-64) - sc-67392 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PARD6B (H-64): sc-67392. Western blot analysis of PARD6B expression in HeLa (A), Caki-1 (B), MIA PaCa-2 (C), JAR (D) PC-3 (E) and Jurkat (F) whole cell lysates.

PARD6B (C-20) - sc-54928 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PARD6B (B-10) - sc-166405 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PARD6B (B-10): sc-166405. Western blot analysis of PARD6B expression in HeLa (A) and NIH/3T3 (B) whole cell lysates.

PARD6B (M-64) - sc-67393 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PARD6B (M-64): sc-67393. Western blot analysis of PARD6B expression in HeLa (A), Caki-1 (B), MIA PaCa-2 (C), JAR (D), PC-3 (E) and Jurkat (F) whole cell lysates.

Anti-PARD6B antibody - ab57838 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
PARD6B antibody (ab57838) used in immunofluorescence at 10ug/ml on HeLa cells.

Anti-PARD6B antibody - ab172893 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-PARD6B antibody (ab172893) at 1/500 dilutionLane 1 : PARD6B-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-PARD6B antibody - Aminoterminal end - ab53230 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PAR6B / PARD6B Antibody (N-Terminus) - LS-C93054 from LifeSpan Bioscience

Prices $575.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PAR6B / PARD6B Antibody (N-Terminus) - LS-C144661 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PAR6B / PARD6B Antibody (N-Terminus) - LS-C82455 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PAR6B / PARD6B Antibody (aa233-282) - LS-C199411 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from Jurkat cells, using PARD6B Antibody. The lane on the right was incubated with synthetic peptide.

Anti-PAR6B / PARD6B Antibody (aa21-70) - LS-C201429 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Mouse Heart. Pard6b antibody dilution 1.0 ug/ml.

PARD6B Antibody - NBP1-87337 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PARD6B Antibody - NBP2-19695 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PARD6B Antibody [NBP2-19695] - Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE gel, diluted at 1:1000.

PARD6B Antibody (1C4) - H00084612-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C4
Western Blot: PARD6B Antibody (1C4) [H00084612-M01] - Analysis of PARD6B expression in transfected 293T cell line by PARD6B monoclonal antibody (M01), clone 1C4.Lane 1: PARD6B transfected lysate(41.2 KDa).Lane 2: Non-transfected lysate.

PARD6B Antibody - H00084612-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PARD6B Antibody [H00084612-B01] - analysis of PARD6B expression in transfected 293T cell line by PARD6B MaxPab polyclonal antibody. Lane 1: PARD6B transfected lysate (40.92 KDa). Lane 2: Non-transfected lysate.

PARD6B Antibody - H00084612-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Rabbit Anti-PARD6B Polyclonal Antibody - bs-7820R from Bioss

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded mouse kidney labeled with Rabbit Anti PARD6B Polyclonal Antibody, Unconjugated (bs-7820R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-PARD6B antibody produced in rabbit - SAB2101718 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PARD6B: <B>Cat. No.SAB2101718</B>: PARD6B in 721_B cell lysate with PARD6B antibody at 1.0 μg/mL.

Anti-Par6β (C-terminal) antibody produced in rabbit - B8187 from Sigma-Aldrich

Prices $57.50, $332.50
Sizes 25 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Nuclear and cell cell contacts localization of PAR6β in MDCK cells. Fixed cells were stained with 2 μg/mL Rabbit Anti-PAR6β (C-terminal) (<B>Cat. No. B8187</B>) followed by Goat Anti-Rabbit IgG, Cy3 conjugate and counterstained with DAPI (blue) to stain nuclei (x40 magnification).

Anti-PARD6B antibody produced in rabbit - HPA013376 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PARD6B: <B>Cat. No. HPA013376</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human duodenum shows cytoplasmic positivity in glandular cells.

Anti-Par6β antibody produced in rabbit - B8062 from Sigma-Aldrich

Prices $57.50, $332.50
Sizes 25 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Nuclear and cell cell contacts localization of PAR6β in MDCK cells. Fixed cells were stained with 2 μg/mL Rabbit Anti-PAR6β (<B>Cat. No. B8062</B>) followed by Goat Anti-Rabbit IgG, Cy3 conjugate and counterstained with DAPI (blue) to stain nuclei (x40 magnification).

PARD6B antibody - N-terminal region (ARP42919_P050) - ARP42919_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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