PARD6B

Gene Symbol PARD6B
Entrez Gene 84612
Alt Symbol PAR6B
Species Human
Gene Type protein-coding
Description par-6 family cell polarity regulator beta
Other Description PAR-6 beta|par-6 partitioning defective 6 homolog beta|partitioning defective 6 homolog beta
Swissprots Q9BYG5 Q9Y510 A2A2A7
Accessions EAW75615 EAW75616 EAW75617 Q9BYG5 AB044555 BAB40756 AB178534 BAF92013 BC060847 AAH60847 CA435324 HQ448524 ADQ33003 NM_032521 NP_115910
Function Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Subcellular Location Cytoplasm. Cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}.
Tissue Specificity Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
Top Pathways Tight junction, Endocytosis, Hippo signaling pathway, Rap1 signaling pathway

PARD6B CRISPR/Cas9 KO Plasmid (h) - sc-401699 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARD6B HDR Plasmid (h) - sc-401699-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARD6B Double Nickase Plasmid (h) - sc-401699-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARD6B Double Nickase Plasmid (h2) - sc-401699-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARD6B CRISPR Activation Plasmid (h) - sc-401699-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARD6B CRISPR Activation Plasmid (h2) - sc-401699-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARD6B Lentiviral Activation Particles (h) - sc-401699-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARD6B Lentiviral Activation Particles (h2) - sc-401699-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARD6B siRNA (h) - sc-62751 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PARD6B shRNA Plasmid (h) - sc-62751-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PARD6B shRNA (h) Lentiviral Particles - sc-62751-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PARD6B RNAi - H00084612-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU015681 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16335 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16335 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PARD6B siRNA (Human) - CRJ3530 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PARD6B (NM_032521.2) - SHH370692 from Creative biogene

Category siRNA
Species Reactivities Human

Human PARD6B siRNA - orb274031 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PARD6B shRNA Plasmid (Human) - CHJ3530 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PARD6B miRNA 3'UTR clone - MiUTR1H-07513 from Creative biogene

Species Reactivities Human
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