SIGLEC11

Gene Symbol	SIGLEC11
Entrez Gene	114132
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	sialic acid binding Ig-like lectin 11
Other Description	sialic acid-binding Ig-like lectin 11|siglec-11
Swissprots	Q96RL6
Accessions	EAW52584 EAW52585 EAW52586 EAW52587 Q96RL6 AB072038 BAB86816 AF337818 AAK72907 AY358135 AAQ88502 BC156822 AAI56823 XM_005258476 XP_005258533 XM_005258477 XP_005258534 XR_243888 NM_001135163 NP_001128635 NM_052884 NP_443116
Function	Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8- linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Siglec-11 (L-13) - sc-131070 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Siglec-11 (P-14) - sc-131072 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-SIGLEC11 antibody - ab106390 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 antibody - ab198707 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 antibody - ab59943 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 antibody - ab59944 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 antibody [EPR8506(2)] - ab157187 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR8506(2)

Anti-SIGLEC11 Antibody (PE) - LS-C182950 from LifeSpan Bioscience Prices $635.00 Sizes 100 tst Host Goat Clonality Polyclonal

Anti-SIGLEC11 Antibody (N-Terminus, APC) - LS-C240781 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (N-Terminus, Biotin) - LS-C240779 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (N-Terminus, AP) - LS-C240778 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (N-Terminus, FITC) - LS-C240782 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (N-Terminus, PE) - LS-C240783 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (C-Terminus, AP) - LS-C245856 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (C-Terminus, PE) - LS-C245863 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (C-Terminus, APC) - LS-C245857 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (C-Terminus, FITC) - LS-C245860 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (C-Terminus) - LS-C328668 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (C-Terminus, Biotin) - LS-C245859 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (C-Terminus, Azide-free, HRP) - LS-C247868 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (N-Terminus, Azide-free, HRP) - LS-C248157 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (N-Terminus) - LS-C330129 from LifeSpan Bioscience Prices $435.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SIGLEC11 Antibody (C-Terminus) - LS-C108509 from LifeSpan Bioscience Prices $345.00, $1,035.00 Sizes 100 µg, 500 µg Host Rabbit Clonality Polyclonal

Siglec-11 Antibody - AF3258 from Novus Biologicals Prices $99.00, $329.00 Sizes 25 µg, 100 µg Host Goat Clonality Polyclonal

Siglec-11 Antibody - NBP2-32523 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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