SIGLEC11

Gene Symbol	SIGLEC11
Entrez Gene	114132
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	sialic acid binding Ig-like lectin 11
Other Description	sialic acid-binding Ig-like lectin 11|siglec-11
Swissprots	Q96RL6
Accessions	EAW52584 EAW52585 EAW52586 EAW52587 Q96RL6 AB072038 BAB86816 AF337818 AAK72907 AY358135 AAQ88502 BC156822 AAI56823 XM_005258476 XP_005258533 XM_005258477 XP_005258534 XR_243888 NM_001135163 NP_001128635 NM_052884 NP_443116
Function	Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8- linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SIGLEC11 Antibody Blocking Peptide - LS-E30695 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Siglec-11 Peptide - NBP1-77025PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

Siglec11 Peptide - GTX85285-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Recombinant Human Siglec-11 Fc Chimera, CF - 3258-SL-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived

SIGLEC11 Control Peptide - AP30780CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Siglec11 Peptide - 5151P from ProSci Category Peptide Species Human

Recombinant Human SIGLEC11, Fc Chimera - SIGLEC11-376H from Creative Biomart Category Protein Source CHO cells Species Human

Recombinant Human Sialic acid-binding Ig-like lectin 11(SIGLEC11) - CSB-YP836293HU CSB-EP836293HU CSB-BP836293HU CSB-MP836293HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Siglec-11 Fc Chimera Protein, CF - 3258-SL from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Human Siglec-11 Asn17-His543 (Glu84Ala & Lys145Gln) Accession # AAK72907 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus Species Human

Siglec-11 Protein - NBP2-32523PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SIGLEC11-Antibody-N-term-Blocking-Peptide - BP1630a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SIGLEC11-Antibody-C-term-Blocking-Peptide - BP1629b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SIGLEC11-Antibody-N-term-Blocking-Peptide - BP1629a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SIGLEC11 Peptide, Human - M34GP14239H from Creative Peptides Category Peptide Source Synthetic. Species Human

Sialic acid-binding Ig-like lectin 11 (SIGLEC11), Recombinant Protein - MBS1431469 from MyBioSource Category Protein Prices $1,325.00, $1,325.00, $1,545.00, $1,545.00, $2,190.00, $2,190.00, $2,655.00, $2,655.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human Siglec-11 Fc Chimera Protein, CF - 3258-SL from Novus Biologicals Category Protein Prices $329.00 Sizes 50 µg Species Human

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