SIGLEC11

Gene Symbol SIGLEC11
Entrez Gene 114132
Alt Symbol -
Species Human
Gene Type protein-coding
Description sialic acid binding Ig-like lectin 11
Other Description sialic acid-binding Ig-like lectin 11|siglec-11
Swissprots Q96RL6
Accessions EAW52584 EAW52585 EAW52586 EAW52587 Q96RL6 AB072038 BAB86816 AF337818 AAK72907 AY358135 AAQ88502 BC156822 AAI56823 XM_005258476 XP_005258533 XM_005258477 XP_005258534 XR_243888 NM_001135163 NP_001128635 NM_052884 NP_443116
Function Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8- linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia.

Siglec-11 CRISPR/Cas9 KO Plasmid (h) - sc-409006 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-11 HDR Plasmid (h) - sc-409006-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-11 Double Nickase Plasmid (h) - sc-409006-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-11 Double Nickase Plasmid (h2) - sc-409006-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-11 CRISPR Activation Plasmid (h) - sc-409006-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-11 CRISPR Activation Plasmid (h2) - sc-409006-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-11 Lentiviral Activation Particles (h) - sc-409006-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-11 Lentiviral Activation Particles (h2) - sc-409006-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-11 siRNA (h) - sc-97277 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Siglec-11 shRNA Plasmid (h) - sc-97277-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Siglec-11 shRNA (h) Lentiviral Particles - sc-97277-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU128001 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN19328 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19328 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SIGLEC11 siRNA (Human) - CRJ4351 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SIGLEC11 - MBS827158 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SIGLEC11 (NM_052884.2) - SHH407440 from Creative biogene

Category siRNA
Species Reactivities Human

Human SIGLEC11 siRNA - orb274852 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SIGLEC11 shRNA Plasmid (Human) - CHJ4351 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SIGLEC11 miRNA 3'UTR clone - MiUTR3H-09009 from Creative biogene

Species Reactivities Human

SIGLEC11 miRNA 3'UTR clone - MiUTR3H-09010 from Creative biogene

Species Reactivities Human
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