NRROS

Gene Symbol NRROS
Entrez Gene 375387
Alt Symbol ELLP3030, GARPL1, LRRC33, UNQ3030
Species Human
Gene Type protein-coding
Description negative regulator of reactive oxygen species
Other Description leucine-rich repeat-containing protein 33
Swissprots Q86YC3
Accessions Q86YC3 AA534416 AY358322 AAQ88688 BC034704 BC044233 AAH44233 BQ070837 HY084054 NM_198565 NP_940967
Function Negative regulator of reactive oxygen species (ROS) that limits ROS production by phagocytes during inflammatory response, thereby playing a role during host defense. Acts via direct interaction with CYBB/NOX2 monomer that impairs interaction between CYBB/NOX2 and CYBA/p22-phox and formation of a stable NOX2 complex (By similarity). May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production. {ECO:0000250, ECO:0000269|PubMed:23545260}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:23545260}; Single-pass type I membrane protein {ECO:0000269|PubMed:23545260}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Ubiquitous, with high level of expression found in bone marrow, thymus, liver, lung, intestine and spleen. {ECO:0000269|PubMed:23545260}.

LRRC33 (N-12) - sc-99545 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-LRRC33 antibody - ab90303 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-LRRC33 antibody (ab90303) at 1 µg/ml (in 5% skim milk / PBS buffer) + PANC-1 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-LRRC33 antibody - ab90358 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LRRC33 antibody (ab90358) at 1/2000 dilutionLane 1 : Untransfected Phoenix Eco whole cell lysate.Lane 2 : Phoenix Eco whole cell lysate. hLRRC33 overexpressionLane 3 : Phoenix Eco whole cell lysate. mLRRC33 overexpressionLysates/proteins at 30 µg per lane.SecondaryHRP-conjugated goat anti-rabbit IgG polyclonal at 1/2000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-NRROS / LRRC33 Antibody (aa611-640, APC) - LS-C237233 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NRROS / LRRC33 Antibody (aa611-640, AP) - LS-C237234 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NRROS / LRRC33 Antibody (aa611-640, Biotin) - LS-C237235 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NRROS / LRRC33 Antibody (aa611-640, FITC) - LS-C237236 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NRROS / LRRC33 Antibody (aa618-648, PE) - LS-C237241 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NRROS / LRRC33 Antibody (aa611-640, Azide-free, HRP) - LS-C248731 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NRROS / LRRC33 Antibody (aa179-228) - LS-C111744 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LRRC33 antibody LS-C111744 Western blot of PANC1 cell lysate.

Anti-NRROS / LRRC33 Antibody (aa611-640) - LS-C329777 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NRROS / LRRC33 Antibody (aa359-408) - LS-C111745 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LRRC33 antibody LS-C111745 Western blot of Fetal Kidney lysate.

Anti-NRROS / LRRC33 Antibody (aa611-640) - LS-C165877 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
LRRC33 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lymph node followed by peroxidase-conjugated secondary antibody and DAB staining.

LRRC33 Antibody - NBP1-90478 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: LRRC33 Antibody [NBP1-90478] - Staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells.

Anti-LRRC33 antibody produced in rabbit - SAB2103948 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LRRC33, antibody produced in rabbit: <B>Cat. No. SAB2103948</B>: Immunoblotting analysis of LRRC33 in fetal kidney tissue lysate with LRRC33 anitbody at 1 μg/mL.

Anti-LRRC33, (N-terminal) antibody produced in rabbit - SAB2103947 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LRRC33, antibody produced in rabbit: <B>Cat. No. SAB2103947</B>: Immunoblotting analysis of LRRC33 in PANC1 cell lysate with LRRC33 anitbody at 1 μg/mL.

LRRC33 antibody - N-terminal region (ARP55907_P050) - ARP55907_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LRRC33 antibody - middle region (ARP55908_P050) - ARP55908_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LRRC33 Antibody - C-terminal region (OAAB00322) - OAAB00322 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

LRRC33-Antibody-C-term - AP10317b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
LRRC33 Antibody (C-term) (Cat. #AP10317b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the LRRC33 antibody detected the LRRC33 protein (arrow).

LRRC33 antibody, Internal - GTX45158 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

LRRC33 antibody, N-term - GTX45159 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

LRRC33 antibody - 70R-7519 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti -LRRC33, CT (LRRC33, Leucine-rich repeat-containing protein 33) - 037950 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -LRRC33, CT (LRRC33, Leucine-rich repeat-containing protein 33) (AP) - 037950-AP from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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