CRLS1

Gene Symbol CRLS1
Entrez Gene 54675
Alt Symbol C20orf155, CLS, CLS1, GCD10, dJ967N21.6
Species Human
Gene Type protein-coding
Description cardiolipin synthase 1
Other Description cardiolipin synthase (CMP-forming)
Swissprots Q69YQ5 E9PAT4 Q27RP0 D3DW09 Q9UJA2
Accessions EAX10399 EAX10400 EAX10401 EAX10402 Q9UJA2 AF241784 AAG44472 AK310368 AL832419 CAH10649 BC069010 AAH69010 BM763234 BP368984 DQ386730 ABD46888 XM_005260737 XP_005260794 XM_005260738 XP_005260795 XM_006723579 XP_006723642 XM_006723580 XP_006723643 XM_011529262 XP_011527564 XM_011529263 XP_011527565 XM_011529264 XP_011527566 XM_011529265 XP_011527567 NM_001127458 NP_001120930 NM_019095 NP_061968
Function Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. {ECO:0000269|PubMed:16547353, ECO:0000269|PubMed:16678169}.
Subcellular Location Mitochondrion inner membrane {ECO:0000269|PubMed:16547353}; Multi-pass membrane protein {ECO:0000269|PubMed:16547353}.
Tissue Specificity Highly expressed in tissues such as heart, skeletal muscle and liver. {ECO:0000269|PubMed:16547353}.
Top Pathways Glycerophospholipid metabolism

CLS1 CRISPR/Cas9 KO Plasmid (h) - sc-407799 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLS1 HDR Plasmid (h) - sc-407799-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLS1 Double Nickase Plasmid (h) - sc-407799-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLS1 Double Nickase Plasmid (h2) - sc-407799-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLS1 CRISPR Activation Plasmid (h) - sc-407799-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLS1 CRISPR Activation Plasmid (h2) - sc-407799-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLS1 Lentiviral Activation Particles (h) - sc-407799-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLS1 Lentiviral Activation Particles (h2) - sc-407799-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLS1 siRNA (h) - sc-72929 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLS1 shRNA Plasmid (h) - sc-72929-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLS1 shRNA (h) Lentiviral Particles - sc-72929-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU020281 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6585 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6585 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01792 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01792

CRLS1 siRNA (Human) - CRJ0172 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRLS1 - MBS8219668 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CRLS1 (NM_019095.4) - SHH269697 from Creative biogene

Category siRNA
Species Reactivities Human

Human CRLS1 siRNA - orb270673 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRLS1 shRNA Plasmid (Human) - CHJ0172 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CRLS1 miRNA 3'UTR clone - MiUTR4H-TG02358 from Creative biogene

Species Reactivities Human
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