Gene Symbol | DEPDC1 |
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Entrez Gene | 55635 |
Alt Symbol | DEP.8, DEPDC1-V2, DEPDC1A, SDP35 |
Species | Human |
Gene Type | protein-coding |
Description | DEP domain containing 1 |
Other Description | DEP domain-containing protein 1A|cell cycle control protein SDP35 |
Swissprots | Q5TB30 Q9NX21 A8QXE1 Q5TB28 Q05DU3 A8QXE0 Q9NXZ0 Q9H9I3 |
Accessions | CAL40387 CAL40388 CAX21632 CAX21633 EAX06471 EAX06472 EAX06473 EAX06474 EAX06475 EAX06476 EAX06477 Q5TB30 AB281187 BAF91373 AB281274 BAF91374 AJ278112 CAB92444 AK000361 BAA91111 AK000490 BAA91201 AK022792 BAB14246 AK225735 AK299324 BAH13001 AL834208 CAH10663 BC003511 AAH03511 BC011743 BC035506 BC041580 BC065304 AAH65304 BU588593 DB147703 NM_001114120 NP_001107592 NM_017779 NP_060249 |
Function | May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. {ECO:0000269|PubMed:20587513}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17452976, ECO:0000269|PubMed:20587513}. Note=Colocalizes with ZNF224 at the nucleus. |
Tissue Specificity | Expressed in testis. Up-regulated in bladder cancer cells (at protein level). {ECO:0000269|PubMed:17452976}. |
DEPDC1 (N-13) - sc-164169 from Santa Cruz Biotechnology
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DEPDC1 (V-14) - sc-164170 from Santa Cruz Biotechnology
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Anti-DEPDC1 antibody - ab197246 from Abcam
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Anti-DEPDC1 antibody - ab107941 from Abcam
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Anti-DEPDC1 antibody - ab183620 from Abcam
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Anti-DEPDC1 Antibody (aa10-38, AP) - LS-C234531 from LifeSpan Bioscience
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Anti-DEPDC1 Antibody (aa10-38, APC) - LS-C234532 from LifeSpan Bioscience
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Anti-DEPDC1 Antibody (aa10-38, Biotin) - LS-C234533 from LifeSpan Bioscience
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Anti-DEPDC1 Antibody (aa10-38, FITC) - LS-C234534 from LifeSpan Bioscience
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Anti-DEPDC1 Antibody (aa10-38, PE) - LS-C234535 from LifeSpan Bioscience
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Anti-DEPDC1 Antibody (aa287-336) - LS-C117190 from LifeSpan Bioscience
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Anti-DEPDC1 Antibody (aa10-38, Azide-free, HRP) - LS-C249818 from LifeSpan Bioscience
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Anti-DEPDC1 Antibody (aa93-187) - LS-C307215 from LifeSpan Bioscience
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Anti-DEPDC1 Antibody (aa17-46) - LS-C320808 from LifeSpan Bioscience
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Anti-DEPDC1 Antibody (aa10-38) - LS-C167364 from LifeSpan Bioscience
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DEPDC1A Antibody - 26630002 from Novus Biologicals
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DEPDC1A Antibody (6H1) - H00055635-M05 from Novus Biologicals
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DEPDC1 Polyclonal Antibody - bs-6525R from Bioss
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ANTI-DEPDC1 (N-TERM) antibody produced in rabbit - SAB1303485 from Sigma-Aldrich
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Anti-DEPDC1 antibody produced in rabbit - SAB2107180 from Sigma-Aldrich
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DEPDC1 antibody - middle region (ARP56317_P050) - ARP56317_P050 from Aviva Systems Biology
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DEPDC1A Antibody - N-terminal region (OAAB02843) - OAAB02843 from Aviva Systems Biology
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DEPDC1-Antibody-N-term - AP5428a from Abgent, a WuXi AppTec company
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DEPDC1 antibody [C2C3], C-term - GTX117924 from GeneTex
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DEPDC1 antibody [N1N3] - GTX117925 from GeneTex
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