DEPDC1

Gene Symbol	DEPDC1
Entrez Gene	55635
Alt Symbol	DEP.8, DEPDC1-V2, DEPDC1A, SDP35
Species	Human
Gene Type	protein-coding
Description	DEP domain containing 1
Other Description	DEP domain-containing protein 1A|cell cycle control protein SDP35
Swissprots	Q5TB30 Q9NX21 A8QXE1 Q5TB28 Q05DU3 A8QXE0 Q9NXZ0 Q9H9I3
Accessions	CAL40387 CAL40388 CAX21632 CAX21633 EAX06471 EAX06472 EAX06473 EAX06474 EAX06475 EAX06476 EAX06477 Q5TB30 AB281187 BAF91373 AB281274 BAF91374 AJ278112 CAB92444 AK000361 BAA91111 AK000490 BAA91201 AK022792 BAB14246 AK225735 AK299324 BAH13001 AL834208 CAH10663 BC003511 AAH03511 BC011743 BC035506 BC041580 BC065304 AAH65304 BU588593 DB147703 NM_001114120 NP_001107592 NM_017779 NP_060249
Function	May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. {ECO:0000269|PubMed:20587513}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:17452976, ECO:0000269|PubMed:20587513}. Note=Colocalizes with ZNF224 at the nucleus.
Tissue Specificity	Expressed in testis. Up-regulated in bladder cancer cells (at protein level). {ECO:0000269|PubMed:17452976}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DEPDC1 protein fragment - ab153404 from Abcam Category Protein Source Wheat germ Species Human

DEPDC1 Antibody Blocking Peptide - LS-E20421 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DEPDC1A Partial Recombinant Protein - H00055635-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

DEPDC1 Blocking Peptide - 33R-7055 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DEPDC1A - H00055635-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DEPDC1A - H00055635-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DEPDC1 fusion protein - ag11787 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DEPDC1 fusion protein - Ag12019 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human DEPDC1, GST-tagged - DEPDC1-120H from Creative Biomart Category Protein Source wheat germ

Recombinant Human DEP domain-containing protein 1A(DEPDC1) ,partial - CSB-YP722576HU CSB-EP722576HU CSB-BP722576HU CSB-MP722576HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DEPDC1-Blocking-Peptide-N-term - BP5428a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DEPDC1 Peptide, Human - M34GP04223H from Creative Peptides Category Peptide Source Synthetic. Species Human

DEPDC1 peptide - orb12932 from Biorbyt Category Peptide Prices $170.00 Sizes 1 mg

DEP domain-containing protein 1A (DEPDC1), partial, Recombinant Protein - MBS1435980 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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