SLU7

Gene Symbol SLU7
Entrez Gene 10569
Alt Symbol 9G8, hSlu7
Species Human
Gene Type protein-coding
Description SLU7 splicing factor homolog (S. cerevisiae)
Other Description pre-mRNA-splicing factor SLU7|splicing factor|step II splicing factor SLU7|zinc knuckle motif containing
Swissprots Q96FM9 Q3LUJ1 D3DQK2 O95391 Q6RXQ5 Q3LUJ0
Accessions EAW61554 EAW61555 EAW61556 O95391 AF101074 AAD13774 AK000813 AK024875 AK314564 BAG37147 AY486334 AAS59410 BC010634 AAH10634 BE221264 CA976106 DA232975 DA409854 DQ174516 ABA08382 DQ174517 ABA08383 DQ891037 ABM81963 DQ894216 ABM85142 XM_005265793 XP_005265850 XM_011534418 XP_011532720 NM_006425 NP_006416
Function Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'- splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. {ECO:0000269|PubMed:10197984, ECO:0000269|PubMed:10647016, ECO:0000269|PubMed:12764196, ECO:0000269|PubMed:15728250}.
Subcellular Location Nucleus. Cytoplasm. Note=Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing. Translocates from the nucleus to the cytoplasm after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.
Top Pathways Spliceosome

SLU7 (B-11) - sc-376985 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SLU7 (B-11): sc-376985. Western blot analysis of SLU7 expression in non-transfected: sc-110760 (A) and human SLU7 transfected: sc-111150 (B) 293 whole cell lysates.

SLU7 (G-3) - sc-393664 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SLU7 (G-3): sc-393664. Western blot analysis of SLU7 expression in non-transfected: sc-110760 (A) and human SLU7 transfected: sc-111150 (B) 293 whole cell lysates and HeLa (C), BJAB (D), MCF7 (E) and Y79 (F) nuclear extracts.

SLU7 (G-12) - sc-393743 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SLU7 (G-12): sc-393743. Western blot analysis of SLU7 expression in non-transfected: sc-110760 (A) and human SLU7 transfected: sc-111150 (B) 293 whole cell lysates and HeLa (C) and BJAB (D) nuclear extracts.

SLU7 (D-6) - sc-365660 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SLU7 (D-6): sc-365660. Western blot analysis of SLU7 expression in HeLa whole cell lysate.

SLU7 (N-18) - sc-10828 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SLU7 (N-18): sc-10828. Western blot analysis of SLU7 expression in non-transfected: sc-110760 (A) and human SLU7 transfected: sc-111150 (B) 293 whole cell lysates.

SLU7 (L-16) - sc-10829 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SLU7 (L-16): sc-10829. Western blot analysis of SLU7 expression in non-transfected: sc-110760 (A) and human SLU7 transfected: sc-111150 (B) 293 whole cell lysates.

SLU7 (C-20) - sc-10831 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SLU7 (C-20): sc-10831. Western blot analysis of SLU7 expression in non-transfected: sc-110760 (A) and human SLU7 transfected: sc-111150 (B) 293 whole cell lysates.

SLU7 (H-180) - sc-292633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SLU7 antibody - ab56710 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56710 SLU7 antibody at 1ug/ml.

Anti-SLU7 antibody - ab137209 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SLU7 antibody (ab137209) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-SLU7 antibody [EPR11111] - ab181138 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11111
All lanes : Anti-SLU7 antibody [EPR11111] (ab181138) at 1/2000 dilutionLane 1 : HeLa cell lysateLane 2 : 293 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-SLU7 / 9G8 Antibody (aa60-86, AP) - LS-C207662 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLU7 / 9G8 Antibody (aa60-86, APC) - LS-C207663 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLU7 / 9G8 Antibody (aa60-86, Biotin) - LS-C207665 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLU7 / 9G8 Antibody (aa60-86, FITC) - LS-C207666 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLU7 / 9G8 Antibody (aa60-86, Azide-free, HRP) - LS-C207667 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLU7 / 9G8 Antibody (aa60-86, PE) - LS-C207668 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLU7 / 9G8 Antibody (aa154-199) - LS-C313956 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLU7 / 9G8 Antibody (aa95-144) - LS-C200705 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using SLU7 antibody.

Anti-SLU7 / 9G8 Antibody (aa59-86) - LS-C325185 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLU7 / 9G8 Antibody (aa35-84) - LS-C111380 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SLU7 antibody LS-C111380 Western blot of HeLa lysate.

Anti-SLU7 / 9G8 Antibody (aa202-251) - LS-C146515 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SLU7 antibody LS-C146515 Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.

Anti-SLU7 / 9G8 Antibody (aa113-162) - LS-C120246 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HeLa cells, using SLU7 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-SLU7 / 9G8 Antibody (aa60-86) - LS-C159038 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SLU7 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The SLU7 Antibody detected the SLU7 protein (arrow).

SLU7 Antibody - NBP2-20403 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SLU7 Antibody [NBP2-20403] - Sample (30 ug of whole cell lysate) A: Non-transfected 293T lysates, B: hSLU7 transfected 293T lysates 7. 5% SDS PAGE gel, diluted at 1:10000.
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