SLU7

Gene Symbol SLU7
Entrez Gene 10569
Alt Symbol 9G8, hSlu7
Species Human
Gene Type protein-coding
Description SLU7 splicing factor homolog (S. cerevisiae)
Other Description pre-mRNA-splicing factor SLU7|splicing factor|step II splicing factor SLU7|zinc knuckle motif containing
Swissprots Q96FM9 Q3LUJ1 D3DQK2 O95391 Q6RXQ5 Q3LUJ0
Accessions EAW61554 EAW61555 EAW61556 O95391 AF101074 AAD13774 AK000813 AK024875 AK314564 BAG37147 AY486334 AAS59410 BC010634 AAH10634 BE221264 CA976106 DA232975 DA409854 DQ174516 ABA08382 DQ174517 ABA08383 DQ891037 ABM81963 DQ894216 ABM85142 XM_005265793 XP_005265850 XM_011534418 XP_011532720 NM_006425 NP_006416
Function Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'- splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. {ECO:0000269|PubMed:10197984, ECO:0000269|PubMed:10647016, ECO:0000269|PubMed:12764196, ECO:0000269|PubMed:15728250}.
Subcellular Location Nucleus. Cytoplasm. Note=Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing. Translocates from the nucleus to the cytoplasm after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.
Top Pathways Spliceosome

Human SLU7 full length protein - ab161049 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161049 on a 12.5% SDS-PAGE stained with Coomassie Blue.

SLU7 / 9G8 Antibody Blocking Peptide - LS-E5852 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SLU7 / 9G8 Antibody Blocking Peptide - LS-E18738 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SLU7 / 9G8 Antibody Blocking Peptide - LS-E18739 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human SLU7 Protein - H00010569-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

SLU7-Antibody-N-term-Blocking-Peptide - BP18404a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SLU7 Blocking Peptide - 33R-4475 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SLU7 Blocking Peptide - abx063687 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine, Monkey

SLU7 - H00010569-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

SLU7 - H00010569-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

SLU7 fusion protein - Ag2680 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human SLU7, GST-tagged - SLU7-2798H from Creative Biomart

Category Protein
Source E.coli
Species Human

SLU7 Blocking Peptide - CBP2493 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Monkey

SLU7 Peptide - BS5936P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Recombinant Human Pre-mRNA-splicing factor SLU7(SLU7) - CSB-YP021783HU CSB-EP021783HU CSB-BP021783HU CSB-MP021783HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

SLU7 - TP302113 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
SLU7

Pre-mRNA-splicing factor SLU7 (SLU7), Recombinant Protein - MBS1289763 from MyBioSource

Category Protein
Prices $1,015.00, $1,015.00, $1,250.00, $1,250.00, $1,570.00, $1,570.00, $2,035.00, $2,035.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Ashbya gossypii

Pre-mRNA-splicing factor SLU7 (SLU7), Recombinant Protein - MBS1424688 from MyBioSource

Category Protein
Prices $1,115.00, $1,115.00, $1,345.00, $1,345.00, $1,765.00, $1,765.00, $2,230.00, $2,230.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (E-Coli), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Candida

Pre-mRNA-splicing factor SLU7 (SLU7), Recombinant Protein - MBS1380863 from MyBioSource

Category Protein
Prices $1,260.00, $1,260.00, $1,475.00, $1,475.00, $2,050.00, $2,050.00, $2,515.00, $2,515.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell

Pre-mRNA-splicing factor SLU7 (SLU7), Recombinant Protein - MBS1185103 from MyBioSource

Category Protein
Prices $1,385.00, $1,385.00, $1,605.00, $1,605.00, $2,310.00, $2,310.00, $2,755.00, $2,755.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Pre-mRNA-splicing factor SLU7 (SLU7), Recombinant Protein - MBS1341522 from MyBioSource

Category Protein
Prices $1,190.00, $1,190.00, $1,410.00, $1,410.00, $1,915.00, $1,915.00, $2,380.00, $2,380.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Yarrowia

Pre-mRNA-splicing factor slu7 (slu7), Recombinant Protein - MBS1425005 from MyBioSource

Category Protein
Prices $1,250.00, $1,250.00, $1,470.00, $1,470.00, $2,035.00, $2,035.00, $2,500.00, $2,500.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Emericella

Pre-mRNA-splicing factor slu7 (slu7), Recombinant Protein - MBS1387895 from MyBioSource

Category Protein
Prices $1,260.00, $1,260.00, $1,480.00, $1,480.00, $2,055.00, $2,055.00, $2,520.00, $2,520.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Neosartorya

Pre-mRNA-splicing factor SLU7 (SLU7), Recombinant Protein - MBS1324713 from MyBioSource

Category Protein
Prices $1,140.00, $1,140.00, $1,370.00, $1,370.00, $1,810.00, $1,810.00, $2,275.00, $2,275.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Debaryomyces

Pre-mRNA-splicing factor SLU7 (SLU7), Recombinant Protein - MBS1399253 from MyBioSource

Category Protein
Prices $1,105.00, $1,105.00, $1,335.00, $1,335.00, $1,745.00, $1,745.00, $2,210.00, $2,210.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Kluyveromyces
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