CAV1

Gene Symbol	CAV1
Entrez Gene	857
Alt Symbol	BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21
Species	Human
Gene Type	protein-coding
Description	caveolin 1, caveolae protein, 22kDa
Other Description	caveolin-1|cell growth-inhibiting protein 32
Swissprots	Q9UQH6 Q9UGP1 Q9UNG1 Q03135
Accessions	AAB82538 AAD23745 AAD34722 CAB63654 EAL24360 EAW83503 EAW83504 EAW83505 Q03135 AB209926 BAD93163 AB451284 BAG70098 AB451416 BAG70230 AF070648 AF074993 AF172085 AAQ13608 AI878826 AK290871 BAF83560 AK307501 AL133639 AM393679 CAL38555 AY762103 AAX07830 BC006432 BC009685 AAH09685 BC082246 AAH82246 BG170208 BT007143 AAP35807 DA477166 DA943080 DB266251 DQ890647 ABM81573 DQ893827 ABM84753 EF179102 EF649773 ABW22625 EF649774 ABW22626 EU176473 ABW03274 Z18951 CAA79476 NM_001172895 NP_001166366 NM_001172896 NP_001166367 NM_001172897 NP_001166368 NM_001753 NP_001744
Function	May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. {ECO:0000250, ECO:0000269|PubMed:11751885, ECO:0000269|PubMed:17287217}.
Subcellular Location	Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae.
Tissue Specificity	Expressed in muscle and lung, less so in liver, brain and kidney.
Top Pathways	Focal adhesion, Endocytosis, Bacterial invasion of epithelial cells, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CAV1 gene - orb91959 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-CAV1-cDNA-Clone - DC02723 from Abgent, a WuXi AppTec company Prices $240.30 Sizes 10 µg Species Human Accession BC009685

Human CAV1 Gene cDNA clone plasmid - HG11440-M from Sino Biological Species Human

Human Caveolin-1/CAV1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11440-NY from Sino Biological Species Human

Human Caveolin-1/CAV1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11440-CY from Sino Biological Species Human

Human Caveolin-1/CAV1 Gene ORF cDNA clone expression plasmid - HG11440-UT from Sino Biological Species Human

Human Caveolin-1/CAV1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11440-ACG from Sino Biological Species Human

Human Caveolin-1/CAV1 Gene ORF cDNA clone expression plasmid, C-His tag - HG11440-CH from Sino Biological Species Human

Human Caveolin-1/CAV1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11440-NF from Sino Biological Species Human

Human Caveolin-1/CAV1 Gene ORF cDNA clone expression plasmid, N-His tag - HG11440-NH from Sino Biological Species Human

Human Caveolin-1/CAV1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11440-NM from Sino Biological Species Human

Human Caveolin-1/CAV1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11440-CF from Sino Biological Species Human

Human Caveolin-1/CAV1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11440-CM from Sino Biological Species Human

Human CAV1 Gene cDNA Clone (full-length ORF Clone), expression ready, C-OFPSpark tag - HG11440-ACR from Sino Biological Species Human Accession NM_001753.3

CAV1 - CL01321H01 from Elabscience Species Human Accession NM_001172895.1

CAV1 - CL01321H02 from Elabscience Species Human Accession NM_001172896.1

CAV1 - CL01321H03 from Elabscience Species Human Accession NM_001753.4

Human Cav1 ORF Clone(NM_001753) - CDCQ130521 from Creative biogene Species Human Accession Q03135

Human CAV1 ORF Clone (BC009685) - CDCS409032 from Creative biogene Species Human Accession Q03135

Human CAV1 ORF clone (NM_001753.3) - CDCB160375 from Creative biogene Species Human

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