CAV1

Gene Symbol	CAV1
Entrez Gene	857
Alt Symbol	BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21
Species	Human
Gene Type	protein-coding
Description	caveolin 1, caveolae protein, 22kDa
Other Description	caveolin-1|cell growth-inhibiting protein 32
Swissprots	Q9UQH6 Q9UGP1 Q9UNG1 Q03135
Accessions	AAB82538 AAD23745 AAD34722 CAB63654 EAL24360 EAW83503 EAW83504 EAW83505 Q03135 AB209926 BAD93163 AB451284 BAG70098 AB451416 BAG70230 AF070648 AF074993 AF172085 AAQ13608 AI878826 AK290871 BAF83560 AK307501 AL133639 AM393679 CAL38555 AY762103 AAX07830 BC006432 BC009685 AAH09685 BC082246 AAH82246 BG170208 BT007143 AAP35807 DA477166 DA943080 DB266251 DQ890647 ABM81573 DQ893827 ABM84753 EF179102 EF649773 ABW22625 EF649774 ABW22626 EU176473 ABW03274 Z18951 CAA79476 NM_001172895 NP_001166366 NM_001172896 NP_001166367 NM_001172897 NP_001166368 NM_001753 NP_001744
Function	May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. {ECO:0000250, ECO:0000269|PubMed:11751885, ECO:0000269|PubMed:17287217}.
Subcellular Location	Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae.
Tissue Specificity	Expressed in muscle and lung, less so in liver, brain and kidney.
Top Pathways	Focal adhesion, Endocytosis, Bacterial invasion of epithelial cells, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Caveolin-1 peptide (33-44) - ab45751 from Abcam Category Peptide Prices $181.00 Sizes 100 µg Species Human

Human Caveolin-1 full length protein - ab114170 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Caveolin-1 peptide - ab4928 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

Human Caveolin-1 peptide - ab189352 from Abcam Category Peptide Species Human

Mouse Caveolin-1 peptide - ab18607 from Abcam Category Peptide

CAV1 / Caveolin 1 Antibody Blocking Peptide - LS-E10955 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CAV1 / Caveolin 1 Antibody Blocking Peptide - LS-E28650 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CAV1 / Caveolin 1 Antibody Blocking Peptide - LS-E28651 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CAV1 / Caveolin 1 Antibody Blocking Peptide - LS-E28652 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CAV1 / Caveolin 1 Antibody Blocking Peptide - LS-E25900 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Caveolin-1 Protein - H00000857-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CAV1-Antibody-Y14-Blocking-Peptide - BP7767a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Caveolin 1 blocking peptide - GTX89541-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat

Caveolin 1 Immunizing peptide - orb17367 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

CAV1 Blocking Peptide - 33R-6427 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CAV1 Blocking Peptide - 33R-8458 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Caveolin 1 Protein - abx065835 from Abbexa Category Protein Source E.coli Species Human

Caveolin 1 Peptide - AC21-0730-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Caveolin-1 - H00000857-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Caveolin-1 - H00000857-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Caveolin-1 control peptide - SP5142CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

Recombinant Human Caveolin 1, Transfected HEK293 Cell Culture Supernatant - 230-20051-200 from RayBiotech Category Protein Prices $102.00 Sizes 200 µl Source Human Embryonic Kidney 293 (HEK293) Cells Species Human

Caveolin-1 Peptide - 45-027P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

CAV1 fusion protein - ag11463 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CAV1 fusion protein - ag11052 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

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