APPL2

Gene Symbol APPL2
Entrez Gene 55198
Alt Symbol DIP13B
Species Human
Gene Type protein-coding
Description adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
Other Description DCC-interacting protein 13-beta|DIP13 beta|adapter protein containing PH domain, PTB domain and leucine zipper motif 2
Swissprots F5GZG0 F8W1P5 Q8NEU8 Q9NVL2 B7Z4B0 B7Z411 Q8N4R7
Accessions EAW97762 EAW97763 EAW97764 Q8NEU8 AK001521 BAG50931 AK290562 BAF83251 AK293783 BAH11594 AK296610 BAH12397 AK297100 BAH12496 AK310377 AY113704 AAM55530 BC028008 BC033731 AAH33731 DN993818 DQ892107 ABM83033 DQ895301 ABM86227 XM_006719472 XP_006719535 XM_011538530 XP_011536832 XM_011538531 XP_011536833 XM_011538532 XP_011536834 NM_001251904 NP_001238833 NM_001251905 NP_001238834 NM_018171 NP_060641
Function Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction. {ECO:0000269|PubMed:15016378}.
Subcellular Location Early endosome membrane {ECO:0000269|PubMed:15016378}; Peripheral membrane protein {ECO:0000269|PubMed:15016378}. Nucleus {ECO:0000269|PubMed:15016378}. Note=Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
Tissue Specificity High levels in brain, heart, kidney and skeletal muscle. {ECO:0000269|PubMed:11431708}.

APPL2 (D-16) - sc-55068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

APPL2 (A-15) - sc-55067 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

APPL2 (B-12) - sc-398860 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
APPL2 (B-12): sc-398860. Western blot analysis of APPL2 expression in non-transfected: sc-117752 (A) and mouse APPL2 transfected: sc-118502 (B) 293T whole cell lysates.

APPL2 (E-1) - sc-271084 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
APPL2 (E-1): sc-271084. Western blot analysis of APPL2 expression in HS 181.Tes whole cell lysate.

APPL2 (F-2) - sc-398859 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
APPL2 (F-2): sc-398859. Western blot analysis of APPL2 expression in non-transfected: sc-117752 (A) and mouse APPL2 transfected: sc-118502 (B) 293T whole cell lysates.

APPL2 (H-60) - sc-67403 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
APPL2 (H-60): sc-67403. Western blot analysis of APPL2 expression in non-transfected: sc-117752 (A) and human APPL2 transfected: sc-115078 (B) 293T whole cell lysates.

APPL2 (N-16) - sc-55069 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
APPL2 (N-16): sc-55069. Western blot analysis of APPL2 expression in non-transfected: sc-117752 (A) and mouse APPL2 transfected: sc-118502 (B) 293T whole cell lysates.

Anti-DIP13B antibody - ab95196 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DIP13B antibody (ab95196) at 0.2 µg/mlLane 1 : HEK293 cell lysateLane 2 : MDA-MB-231 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat anti-rabbit antibody

Anti-DIP13B antibody - ab169859 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human fetal kidney tissue labelling DIP13B with ab169859 at 1/100 dilution.

Anti-DIP13B antibody - ab67816 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-DIP13B antibody (ab67816) at 1/500 dilutionLane 1 : DIP13B transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-DIP13B antibody - C-terminal - ab154661 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DIP13B antibody - C-terminal (ab154661) at 1/1000 dilutionLane 1 : NT2D1 whole cell lysateLane 2 : IMR32 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-DIP13B antibody - N-terminal - ab173117 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-DIP13B antibody - N-terminal (ab173117) at 1/60 dilutionLane 2 : Anti-DIP13B antibody - N-terminal (ab173117) at 1/250 dilutionLane 1 : NCI-H292 cell line lysateLane 2 : NCI-H292 cell line lysate preincubated with blocking peptide

Anti-APPL2 Antibody (aa124-152, AP) - LS-C232785 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APPL2 Antibody (aa124-152, APC) - LS-C232787 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APPL2 Antibody (aa124-152, Biotin) - LS-C232788 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APPL2 Antibody (aa124-152, FITC) - LS-C232789 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APPL2 Antibody (aa124-152, Azide-free, HRP) - LS-C249447 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APPL2 Antibody (aa124-152, PE) - LS-C232791 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-APPL2 Antibody - LS-C306307 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-APPL2 Antibody (aa174-274) - LS-C307868 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-APPL2 Antibody (aa124-152) - LS-C159098 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of APPL2 Antibody antibody pre-incubated without(lane 1) and with(lane 2) blocking peptide in NCI-H292 cell line lysate. APPL2 Antibody (arrow) was detected using the purified antibody.

Anti-APPL2 Antibody (aa122-152) - LS-C319550 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

DIP13B Antibody - NBP2-16164 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DIP13B Antibody - H00055198-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: DIP13B Antibody [H00055198-B01P] - Analysis of APPL2 expression in rat brain.

DIP13B Antibody - NBP2-14303 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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