APPL2

Gene Symbol APPL2
Entrez Gene 55198
Alt Symbol DIP13B
Species Human
Gene Type protein-coding
Description adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
Other Description DCC-interacting protein 13-beta|DIP13 beta|adapter protein containing PH domain, PTB domain and leucine zipper motif 2
Swissprots F5GZG0 F8W1P5 Q8NEU8 Q9NVL2 B7Z4B0 B7Z411 Q8N4R7
Accessions EAW97762 EAW97763 EAW97764 Q8NEU8 AK001521 BAG50931 AK290562 BAF83251 AK293783 BAH11594 AK296610 BAH12397 AK297100 BAH12496 AK310377 AY113704 AAM55530 BC028008 BC033731 AAH33731 DN993818 DQ892107 ABM83033 DQ895301 ABM86227 XM_006719472 XP_006719535 XM_011538530 XP_011536832 XM_011538531 XP_011536833 XM_011538532 XP_011536834 NM_001251904 NP_001238833 NM_001251905 NP_001238834 NM_018171 NP_060641
Function Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction. {ECO:0000269|PubMed:15016378}.
Subcellular Location Early endosome membrane {ECO:0000269|PubMed:15016378}; Peripheral membrane protein {ECO:0000269|PubMed:15016378}. Nucleus {ECO:0000269|PubMed:15016378}. Note=Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
Tissue Specificity High levels in brain, heart, kidney and skeletal muscle. {ECO:0000269|PubMed:11431708}.

APPL2-Antibody-N-term-Blocking-Peptide - BP17460a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

APPL2 / DIP13B - H00055198-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

APPL2 / DIP13B - H00055198-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

APPL2 / DIP13B - H00055198-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

APPL2 / DIP13B - H00055198-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

APPL2 fusion protein - ag5626 from Proteintech Group

Category Protein
Source E. coli-derived, T-HIS
Species Human

Recombinant Human APPL2, His-tagged - APPL2-28348TH from Creative Biomart

Category Protein
Source E. coli

Recombinant Human APPL2, His-tagged - APPL2-1003H from Creative Biomart

Category Protein
Source E.Coli.

Recombinant Human APPL2 - APPL2-1002H from Creative Biomart

Category Protein
Source Insect.

Recombinant Human DCC-interacting protein 13-beta(APPL2) - CSB-YP818777HU CSB-EP818777HU CSB-BP818777HU CSB-MP818777HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

APPL2 / DIP13B - TP307506 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
APPL2 / DIP13B

DCC-interacting protein 13-beta (APPL2), Recombinant Protein - MBS1379469 from MyBioSource

Category Protein
Prices $1,465.00, $1,465.00, $1,695.00, $1,695.00, $2,495.00, $2,495.00, $2,935.00, $2,935.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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