APPL2

Gene Symbol APPL2
Entrez Gene 55198
Alt Symbol DIP13B
Species Human
Gene Type protein-coding
Description adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
Other Description DCC-interacting protein 13-beta|DIP13 beta|adapter protein containing PH domain, PTB domain and leucine zipper motif 2
Swissprots F5GZG0 F8W1P5 Q8NEU8 Q9NVL2 B7Z4B0 B7Z411 Q8N4R7
Accessions EAW97762 EAW97763 EAW97764 Q8NEU8 AK001521 BAG50931 AK290562 BAF83251 AK293783 BAH11594 AK296610 BAH12397 AK297100 BAH12496 AK310377 AY113704 AAM55530 BC028008 BC033731 AAH33731 DN993818 DQ892107 ABM83033 DQ895301 ABM86227 XM_006719472 XP_006719535 XM_011538530 XP_011536832 XM_011538531 XP_011536833 XM_011538532 XP_011536834 NM_001251904 NP_001238833 NM_001251905 NP_001238834 NM_018171 NP_060641
Function Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction. {ECO:0000269|PubMed:15016378}.
Subcellular Location Early endosome membrane {ECO:0000269|PubMed:15016378}; Peripheral membrane protein {ECO:0000269|PubMed:15016378}. Nucleus {ECO:0000269|PubMed:15016378}. Note=Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
Tissue Specificity High levels in brain, heart, kidney and skeletal muscle. {ECO:0000269|PubMed:11431708}.

APPL2 CRISPR/Cas9 KO Plasmid (h) - sc-402991 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APPL2 HDR Plasmid (h) - sc-402991-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APPL2 Double Nickase Plasmid (h) - sc-402991-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APPL2 Double Nickase Plasmid (h2) - sc-402991-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APPL2 CRISPR Activation Plasmid (h) - sc-402991-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APPL2 CRISPR Activation Plasmid (h2) - sc-402991-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APPL2 Lentiviral Activation Particles (h) - sc-402991-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APPL2 Lentiviral Activation Particles (h2) - sc-402991-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APPL2 siRNA (h) - sc-61982 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APPL2 shRNA Plasmid (h) - sc-61982-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APPL2 shRNA (h) Lentiviral Particles - sc-61982-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU066351 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3361 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3361 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

APPL2 siRNA (Human) - CRJ0549 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APPL2 - MBS8226216 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human APPL2 (NM_018171.3) - SHH238762 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human APPL2(NM_018171.3) - SHG066717 from Creative biogene

Category siRNA
Species Reactivities Human

Human APPL2 siRNA - orb271050 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APPL2 shRNA Plasmid (Human) - CHJ0549 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

APPL2 miRNA 3'UTR clone - MiUTR1H-00493 from Creative biogene

Species Reactivities Human
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