Gene Symbol | SPPL2C |
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Entrez Gene | 162540 |
Alt Symbol | IMP5 |
Species | Human |
Gene Type | protein-coding |
Description | signal peptide peptidase like 2C |
Other Description | IMP-5|SPP-like 2C|intramembrane protease 5|signal peptide peptidase-like 2C |
Swissprots | Q8WVZ6 Q8TC67 Q8IUH8 |
Accessions | AAO12541 EAW93564 Q8IUH8 BC022041 AAH22041 BC025401 AAH25401 NM_175882 NP_787078 |
Function | Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305|PubMed:16829952}; Multi-pass membrane protein {ECO:0000305|PubMed:16829952}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16829952}; Multi-pass membrane protein {ECO:0000269|PubMed:16829952}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15385547}. |
IMP5 (N-15) - sc-164665 from Santa Cruz Biotechnology
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Anti-IMP5 antibody - ab98157 from Abcam
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Anti-IMP5 Antibody (C-Terminus) - LS-C345508 from LifeSpan Bioscience
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Anti-IMP5 Antibody (aa575-624) - LS-C107733 from LifeSpan Bioscience
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IMP5 Antibody - NBP1-69690 from Novus Biologicals
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Anti-IMP5 antibody produced in rabbit - SAB2104928 from Sigma-Aldrich
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Anti-SPPL2C antibody produced in rabbit - HPA024444 from Sigma-Aldrich
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SPPL2C Antibody - C-terminal region (ARP53335_P050) - ARP53335_P050 from Aviva Systems Biology
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IMP5 antibody - middle region (ARP53336_P050) - ARP53336_P050 from Aviva Systems Biology
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IMP5 antibody, Internal - GTX45555 from GeneTex
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SPPL2C / IMP5 antibody - 12664-1-AP from Acris Antibodies
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SPPL2C / IMP5 (Center) antibody - AP46141PU-N from Acris Antibodies
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IMP5 antibody - 12664-1-AP from Proteintech Group
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IMP5 Antibody - GWB-MT027I from Genway Biotech
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IMP5 Antibody - EPP14363 from Elabscience
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IMP5-antibody-middle-region-AI13541 - AI13541 from Abgent, a WuXi AppTec company
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SPPL2C / IMP5 (Center) antibody - TA337560 from Acris Antibodies
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SPPL2C antibody - orb325854 from Biorbyt
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Anti-IMP5 (internal region) polyclonal antibody - CABT-BL1933 from Creative Diagnostics
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Anti-SPPL2C Antibody A12664 - A12664 from Boster Bio
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IMP5 Antibody - NBP1-62698 from Novus Biologicals
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SPPL2C Antibody - C-terminal region : Biotin (ARP53335_P050-Biotin) - ARP53335_P050-Biotin from Aviva Systems Biology
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SPPL2C Antibody - C-terminal region : FITC (ARP53335_P050-FITC) - ARP53335_P050-FITC from Aviva Systems Biology
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SPPL2C Antibody - C-terminal region : HRP (ARP53335_P050-HRP) - ARP53335_P050-HRP from Aviva Systems Biology
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IMP5 antibody - middle region : Biotin (ARP53336_P050-Biotin) - ARP53336_P050-Biotin from Aviva Systems Biology
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