| Gene Symbol |
SPPL2C
|
| Entrez Gene |
162540
|
| Alt Symbol |
IMP5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
signal peptide peptidase like 2C
|
| Other Description |
IMP-5|SPP-like 2C|intramembrane protease 5|signal peptide peptidase-like 2C
|
| Swissprots |
Q8WVZ6 Q8TC67 Q8IUH8
|
| Accessions |
AAO12541 EAW93564 Q8IUH8 BC022041 AAH22041 BC025401 AAH25401 NM_175882 NP_787078
|
| Function |
Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane. {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305|PubMed:16829952}; Multi-pass membrane protein {ECO:0000305|PubMed:16829952}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16829952}; Multi-pass membrane protein {ECO:0000269|PubMed:16829952}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:15385547}.
|