Gene Symbol | SPPL2C |
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Entrez Gene | 162540 |
Alt Symbol | IMP5 |
Species | Human |
Gene Type | protein-coding |
Description | signal peptide peptidase like 2C |
Other Description | IMP-5|SPP-like 2C|intramembrane protease 5|signal peptide peptidase-like 2C |
Swissprots | Q8WVZ6 Q8TC67 Q8IUH8 |
Accessions | AAO12541 EAW93564 Q8IUH8 BC022041 AAH22041 BC025401 AAH25401 NM_175882 NP_787078 |
Function | Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305|PubMed:16829952}; Multi-pass membrane protein {ECO:0000305|PubMed:16829952}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16829952}; Multi-pass membrane protein {ECO:0000269|PubMed:16829952}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15385547}. |
Human IMP5 protein fragment - ab165748 from Abcam
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Recombinant Human IMP5 Protein - H00162540-Q01 from Novus Biologicals
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SPPL2C / IMP5 - H00162540-Q01-10 from Acris Antibodies
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SPPL2C / IMP5 - H00162540-Q01-25 from Acris Antibodies
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IMP5 fusion protein - ag9134 from Proteintech Group
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IMP5 fusion protein - Ag3345 from Proteintech Group
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SPPL2C Peptide, Human - M34GP15086H from Creative Peptides
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Signal peptide peptidase-like 2C (SPPL2C), Recombinant Protein - MBS7093137 from MyBioSource
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