AMOTL2

Gene Symbol AMOTL2
Entrez Gene 51421
Alt Symbol LCCP
Species Human
Gene Type protein-coding
Description angiomotin like 2
Other Description Leman coiled-coil protein|angiomotin-like protein 2
Swissprots Q96F99 Q53EP1 E9PHW3 Q9Y2J4 A8K6F1 Q9UKB4 B7Z5Q1
Accessions EAW79150 EAW79151 EAW79152 Q9Y2J4 AA056579 AB023206 BAA76833 AF175966 AAD56361 AI214560 AK001343 AK074731 BAG51994 AK091040 BAG52268 AK223598 BAD97318 AK291616 BAF84305 AK299270 BAH12987 AW294642 BC011454 AAH11454 BC025981 AAH25981 BU178516 DA330301 XM_006713654 XP_006713717 XM_011512877 XP_011511179 XM_011512878 XP_011511180 XM_011512879 XP_011511181 XM_011512880 XP_011511182 XM_011512881 XP_011511183 NM_001278683 NP_001265612 NM_001278685 NP_001265614 NM_016201 NP_057285
Function Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC. {ECO:0000269|PubMed:17293535, ECO:0000269|PubMed:21937427, ECO:0000269|PubMed:22362771}.
Subcellular Location Recycling endosome {ECO:0000250}.

Angiomotin-L2 (A-9) - sc-398261 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Angiomotin-L2 (A-9): sc-398261. Western blot analysis of Angiomotin-L2 expression in non-transfected: sc-110760 (A) and human Angiomotin-L2 transfected: sc-111028 (B) 293 whole cell lysates.

Angiomotin-L2 (D-15) - sc-82499 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Angiomotin-L2 (D-15): sc-82499. Western blot analysis of Angiomotin-L2 expression in NIH/3T3 (A), HEK293 (B) and HeLa (C) whole cell lysates.

Angiomotin-L2 (G-23) - sc-130951 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal

Angiomotin-L2 (H-40) - sc-292655 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Angiomotin-L2 (N-14) - sc-82501 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Angiomotin-L2 (N-14): sc-82501. Western blot analysis of Angiomotin-L2 expression in HeLa whole cell lysate.

Anti-AMOTL2 antibody - ab197818 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling AMOTL2 with ab197818 at 1/20 dilution.

Anti-AMOTL2 antibody - ab135722 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-AMOTL2 antibody (ab135722) at 1/100 dilution + A375 cell line lysate at 35 µg

Anti-AMOTL2 antibody - ab182177 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AMOTL2 Antibody (aa132-161, Biotin) - LS-C243663 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOTL2 Antibody (aa132-161, APC) - LS-C243665 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOTL2 Antibody (aa132-161, AP) - LS-C243664 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOTL2 Antibody (aa132-161, FITC) - LS-C243666 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOTL2 Antibody (aa132-161, PE) - LS-C243668 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOTL2 Antibody (aa132-161, Azide-free, HRP) - LS-C247435 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOTL2 Antibody (aa132-161) - LS-C326829 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOTL2 Antibody (aa132-161) - LS-C156314 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of AMOTL2 Antibody in mouse liver tissue lysates (35 ug/lane). AMOTL2 (arrow) was detected using the purified antibody.

Anti-AMOTL2 Antibody (aa6-235) - LS-C178611 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AMOTL2 antibody produced in rabbit - AV42905 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV42905</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.0 μg/mL in cell type HepG2

Anti-AMOTL2 antibody produced in rabbit - SAB4300977 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-AMOTL2 (CENTER) antibody produced in rabbit - SAB1304596 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-AMOTL2 (Center): <B>Cat. No. SAB1304596</B>: Western blot analysis of AMOTL2 Antibody (Center) in A375 cell line lysates (35 μg/lane).

AMOTL2-Antibody-Center - AP8860c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of AMOTL2 Antibody (Center) (Cat. #AP8860c) in A375 cell line lysates (35ug/lane). AMOTL2 (arrow) was detected using the purified Pab.

AMOTL2 antibody [C1C3] - GTX120057 from GeneTex

Prices $149.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Anti-AMOTL2 antibody [C1C3] used in WB-Ag. GTX120057

AMOTL2 antibody, Internal - GTX80977 from GeneTex

Prices $329.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-AMOTL2 antibody, Internal used in Western blot. GTX80977

AMOTL2 Antibody - middle region (OAAB05455) - OAAB05455 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

AMOTL2 antibody - orb78004 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin embedded fetal heart staining using AMOTL2 antibody
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