AMOTL2

Gene Symbol AMOTL2
Entrez Gene 51421
Alt Symbol LCCP
Species Human
Gene Type protein-coding
Description angiomotin like 2
Other Description Leman coiled-coil protein|angiomotin-like protein 2
Swissprots Q96F99 Q53EP1 E9PHW3 Q9Y2J4 A8K6F1 Q9UKB4 B7Z5Q1
Accessions EAW79150 EAW79151 EAW79152 Q9Y2J4 AA056579 AB023206 BAA76833 AF175966 AAD56361 AI214560 AK001343 AK074731 BAG51994 AK091040 BAG52268 AK223598 BAD97318 AK291616 BAF84305 AK299270 BAH12987 AW294642 BC011454 AAH11454 BC025981 AAH25981 BU178516 DA330301 XM_006713654 XP_006713717 XM_011512877 XP_011511179 XM_011512878 XP_011511180 XM_011512879 XP_011511181 XM_011512880 XP_011511182 XM_011512881 XP_011511183 NM_001278683 NP_001265612 NM_001278685 NP_001265614 NM_016201 NP_057285
Function Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC. {ECO:0000269|PubMed:17293535, ECO:0000269|PubMed:21937427, ECO:0000269|PubMed:22362771}.
Subcellular Location Recycling endosome {ECO:0000250}.

Angiomotin-L2 CRISPR/Cas9 KO Plasmid (h) - sc-402027 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin-L2 HDR Plasmid (h) - sc-402027-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin-L2 Double Nickase Plasmid (h) - sc-402027-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin-L2 Double Nickase Plasmid (h2) - sc-402027-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin-L2 CRISPR Activation Plasmid (h) - sc-402027-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin-L2 CRISPR Activation Plasmid (h2) - sc-402027-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin-L2 Lentiviral Activation Particles (h) - sc-402027-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin-L2 Lentiviral Activation Particles (h2) - sc-402027-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin-L2 siRNA (h) - sc-72493 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Angiomotin-L2 shRNA Plasmid (h) - sc-72493-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Angiomotin-L2 shRNA (h) Lentiviral Particles - sc-72493-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU135381 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3123 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3123 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12934 from Sigma-Aldrich

Category miRNA

AMOTL2 siRNA (Human) - CRH9753 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AMOTL2 - MBS8221692 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AMOTL2 (NM_016201.2) - SHH235882 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AMOTL2(NM_016201.2) - SHG056503 from Creative biogene

Category siRNA
Species Reactivities Human

AMOTL2 shRNA Plasmid (Human) - CHH9753 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AMOTL2 miRNA 3'UTR clone - MiUTR1H-00342 from Creative biogene

Species Reactivities Human
Search more