FOXL2

Gene Symbol	FOXL2
Entrez Gene	668
Alt Symbol	BPES, BPES1, PFRK, PINTO, POF3
Species	Human
Gene Type	protein-coding
Description	forkhead box L2
Other Description	forkhead box protein L2\|forkhead transcription factor FOXL2
Swissprots	P58012 Q4ZGJ3
Accessions	AAQ01519 AAY21821 AAY21822 AAY21823 P58012 AF301906 AAK01352 AI089172 BC019896 AAH19896 BC062549 AAH62549 BF512713 DQ089670 AAY89234 DQ089671 AAY89235 DQ089672 AAY89236 FJ598614 NM_023067 NP_075555
Function	Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans- differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. {ECO:0000250, ECO:0000269\|PubMed:16153597, ECO:0000269\|PubMed:19010791, ECO:0000269\|PubMed:19429596, ECO:0000269\|PubMed:19744555}.
Subcellular Location	Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00089, ECO:0000269\|PubMed:19744555}.
Tissue Specificity	In addition to its expression in the developing eyelid, it is transcribed very early in somatic cells of the developing gonad (before sex determination) and its expression persists in the follicular cells of the adult ovary.

FOXL2 (A-14) - sc-55655 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

FOXL2 (G-15) - sc-55657 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

FOXL2 (G-15): sc-55657. Immunoperoxidase staining of formalin fixed, paraffin-embedded human ovary tissue showing nuclear and cytoplasmic staining of ovarian stroma cells.

FOXL2 (H-43) - sc-68348 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

FOXL2 (H-43): sc-68348. Western blot analysis of FOXL2 expression in Jurkat (A), K-562 (B), HeLa (C) and ACHN (D) whole cell lysates.

FOXL2 (262C1a) - sc-81275 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

FOXL2 (262C1a): sc-81275 Western Blot analysis of human recombinant FOXL2 fusion protein.

Anti-FOXL2 (phospho S263) antibody - ab74144 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-FOXL2 (phospho S263) antibody (ab74144) at 1/500 dilutionLane 1 : K562 cells treated with Na3VO4 (0.3nM, 40mins),Lane 2 : K562 cells treated with Na3VO4 (0.3nM, 40mins), with phosphopeptide at 10 µgLysates/proteins at 5 µg per lane.

Anti-FOXL2 antibody - ab5096 from Abcam

Prices	$391.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Immunohistochemical analysis of paraffin embedded Human Ovary tissue labeling FOXL2 with ab5096 at 2 ug/ml. Tissue underwent antigen retrieval in steam with citrate buffer (pH 6.0). The HRP-staining procedure was used for detection.

Anti-FOXL2 antibody - ab49293 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Lane 1 : Lane 2 : Anti-FOXL2 antibody (ab49293) at 1.25 µg/mlLane 1 : MW markerLane 2 : Jurkat cell lysate at 10 µgSecondaryLane 2 : HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-FOXL2 antibody - ab68339 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-FOXL2 antibody (ab68339) at 1 µg/mlLane 1 : Whole cell lysates prepared from Human MM453 cells.Lane 2 : Whole cell lysates prepared from Human Hela cells.Lane 3 : Whole cell lysates prepared from Human SMMc cells.Lane 4 : Whole cell lysates prepared from Human SW620 cells.Lysates/proteins at 50 µg per lane.SecondaryHRP-conjugated Goat anti-rabbit IgG at 1/3000 dilution

Anti-FOXL2 antibody [262C1a] - ab58622 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	262C1a

Anti-FOXL2 antibody [262C1a] (ab58622) + immunogen (recombinant fragment)

Anti-FOXL2 antibody [EPR4837] - ab188584 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR4837

Anti-FOXL2 antibody [EPR4837] (ab188584) at 1/1000 dilution + Jurkat cell lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-FOXL2 Antibody - LS-C66343 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal

Anti-FOXL2 Antibody (N-Terminus) - LS-C121836 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-FOXL2 Antibody (N-Terminus) - LS-C30899 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-FOXL2 Antibody (N-Terminus, Sepharose) - LS-C171861 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-FOXL2 Antibody (N-Terminus, Magnetic beads) - LS-C171860 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-FOXL2 Antibody (C-Terminus) - LS-C134889 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

FOXL2 antibody LS-C134889 Western blot of Rat Liver lysate.

Anti-FOXL2 Antibody (clone 262C1a) - LS-C184580 from LifeSpan Bioscience

Prices	$335.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	262C1a

Anti-FOXL2 Antibody (aa3-29, Biotin) - LS-C235382 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FOXL2 Antibody (aa3-29, AP) - LS-C235381 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FOXL2 Antibody (aa154-203) - LS-C134890 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

FOXL2 antibody LS-C134890 Western blot of Rat Brain lysate.

Anti-FOXL2 Antibody (aa3-29, FITC) - LS-C235383 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FOXL2 Antibody (aa3-29, APC) - LS-C235384 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FOXL2 Antibody - LS-C48665 from LifeSpan Bioscience

Prices	$410.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of FOXL2 antibody LS-C48665.

Anti-FOXL2 Antibody (aa3-29, Azide-free, HRP) - LS-C249008 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FOXL2 Antibody (aa3-29, PE) - LS-C235386 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

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