FOXL2

Gene Symbol	FOXL2
Entrez Gene	668
Alt Symbol	BPES, BPES1, PFRK, PINTO, POF3
Species	Human
Gene Type	protein-coding
Description	forkhead box L2
Other Description	forkhead box protein L2|forkhead transcription factor FOXL2
Swissprots	P58012 Q4ZGJ3
Accessions	AAQ01519 AAY21821 AAY21822 AAY21823 P58012 AF301906 AAK01352 AI089172 BC019896 AAH19896 BC062549 AAH62549 BF512713 DQ089670 AAY89234 DQ089671 AAY89235 DQ089672 AAY89236 FJ598614 NM_023067 NP_075555
Function	Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans- differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. {ECO:0000250, ECO:0000269|PubMed:16153597, ECO:0000269|PubMed:19010791, ECO:0000269|PubMed:19429596, ECO:0000269|PubMed:19744555}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089, ECO:0000269|PubMed:19744555}.
Tissue Specificity	In addition to its expression in the developing eyelid, it is transcribed very early in somatic cells of the developing gonad (before sex determination) and its expression persists in the follicular cells of the adult ovary.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FOXL2 full length protein - ab152239 from Abcam Category Protein Source Wheat germ Species Human

FOXL2 Antibody Blocking Peptide - LS-E83 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FOXL2 Antibody Blocking Peptide - LS-E25569 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FOXL2 Antibody Blocking Peptide - LS-E14323 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FOXL2 Antibody Blocking Peptide - LS-E11769 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FOXL2 Antibody Blocking Peptide - LS-E11768 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FOXL2 Recombinant Protein - H00000668-P01 from Novus Biologicals Category Protein

FOXL2-Antibody-N-term-Blocking-peptide - BP10166a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FOXL2 blocking peptide - GTX25096-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

FoxL2 Blocking Peptide - 33R-10912 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

FOXL2 Peptide - AC21-0398-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

FOXL2 - H00000668-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

FOXL2 Control Peptide - SP5291CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

FOXL2 Peptide - 45-617P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human Forkhead box protein L2(FOXL2) - CSB-YP008827HU CSB-EP008827HU CSB-BP008827HU CSB-MP008827HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FoxL2 Blocking Peptide - 3742BP-50 from Biovision Category Peptide Prices $95.00 Sizes 50 µg

FOXL2 Peptide - abx164684 from Abbexa Category Peptide Species Human, Mouse, Rat

FOXL2 - TP309127 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

FOXL2/BPES, Peptide - MBS426243 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Bovine

FOXL2 Recombinant Protein Antigen - NBP2-49608PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

FOXL2 Peptide, Human - M34GP05867H from Creative Peptides Category Peptide Source Synthetic. Species Human

Forkhead box protein L2 (FOXL2), Recombinant Protein - MBS954234 from MyBioSource Category Protein Prices $1,145.00, $1,145.00, $1,375.00, $1,375.00, $1,825.00, $1,825.00, $2,290.00, $2,290.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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