TLR7

Gene Symbol	TLR7
Entrez Gene	51284
Alt Symbol	TLR7-like
Species	Human
Gene Type	protein-coding
Description	toll-like receptor 7
Other Description	toll-like receptor 7-like
Swissprots	D1CS69 Q9NR98 Q9NYK1
Accessions	AAZ99021 AAZ99022 AAZ99023 AAZ99024 AAZ99025 AAZ99026 EAW98807 Q9NYK1 AB445659 BAG55056 AF240467 AAF60188 AF245702 AAF78035 AK313858 BAG36586 AY358292 AAQ88659 BC033651 AAH33651 DQ891269 ABM82195 DQ894457 ABM85383 NM_016562 NP_057646
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endosome {ECO:0000250}. Lysosome {ECO:0000250}. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. {ECO:0000250}.
Tissue Specificity	Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.
Top Pathways	Toll-like receptor signaling pathway, Measles, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TLR7 (NP_057646) VersaClone cDNA - RDC0640 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

Mouse TLR7 (NP_573474) VersaClone cDNA - RDC0738 from R&D Systems Prices $499.00 Sizes 10 µg Species Mouse

TLR7 - MBS1270492 from MyBioSource Species Human Accession BC033651

Human TLR7 cDNA clone(NM_016562.3) - CDFH019714 from Creative Biomart Species Human Accession NM_016562.3

Human TLR7 ORF clone(NM_016562.3) - CDCL186482 from Creative Biomart Species Human Accession NM_016562.3

Human TLR7 ORF Clone(NM_016562.3) - CDCR301439 from Creative Biomart Species Human Accession NM_016562.3

Human TLR7 ORF Clone(NM_016562.3) - CDCR301440 from Creative Biomart Species Human Accession NM_016562.3

human TLR7 ORF clone - CDCH091454 from Creative Biomart Species Human Accession NM_016562

human TLR7 ORF clone - CDCH091455 from Creative Biomart Species Human Accession NM_016562

Human TLR7 ORF Clone(NM_016562.3) - CDCL178609 from Creative Biomart Species Human Accession NM_016562.3

Human TLR7 Gene ORF cDNA clone in cloning vector - HG11204-M from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11204-NF from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11204-NM from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11204-CF from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11204-NY from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11204-M-F from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, N-His tag - HG11204-NH from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11204-CM from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, C-His tag - HG11204-CH from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11204-CY from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11204-ACR from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid - HG11204-UT from Sino Biological Species Human

Human TLR7 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11204-ACG from Sino Biological Species Human

Human TLR7 ORF clone(NM_016562.3) - CDCL186482 from Creative biogene Species Human

Human TLR7 ORF Clone (BC033651) - CDCS414335 from Creative biogene Species Human Accession B2R9N9

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