TLR7

Gene Symbol	TLR7
Entrez Gene	51284
Alt Symbol	TLR7-like
Species	Human
Gene Type	protein-coding
Description	toll-like receptor 7
Other Description	toll-like receptor 7-like
Swissprots	D1CS69 Q9NR98 Q9NYK1
Accessions	AAZ99021 AAZ99022 AAZ99023 AAZ99024 AAZ99025 AAZ99026 EAW98807 Q9NYK1 AB445659 BAG55056 AF240467 AAF60188 AF245702 AAF78035 AK313858 BAG36586 AY358292 AAQ88659 BC033651 AAH33651 DQ891269 ABM82195 DQ894457 ABM85383 NM_016562 NP_057646
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endosome {ECO:0000250}. Lysosome {ECO:0000250}. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. {ECO:0000250}.
Tissue Specificity	Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.
Top Pathways	Toll-like receptor signaling pathway, Measles, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TLR7 protein fragment - ab153341 from Abcam Category Protein Source Wheat germ Species Human

Mouse TLR7 peptide - ab40020 from Abcam Category Peptide Species Mouse

TLR7 Antibody Blocking Peptide - LS-E2641 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TLR7 Antibody Blocking Peptide - LS-E3793 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TLR7 Antibody Blocking Peptide - LS-E30055 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human TLR7 Protein - H00051284-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TLR7 Peptide - P0517 from Novus Biologicals Category Peptide Species Human

TLR7-Antibody-C-term-Blocking-peptide - BP13712b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TLR7-Antibody-N-term-Blocking-Peptide - BP1507b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human Toll Like Receptor 7 Protein - abx069373 from Abbexa Category Protein Source E.coli Species Human

TLR7 - H00051284-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TLR7 - H00051284-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TLR7 Control Peptide - AP10346CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 100 µg

TLR7 fusion protein - Ag11120 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

TLR7 fusion protein - ag11073 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human TLR7, His-tagged - TLR7-3260H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Toll Like Receptor 7 (TLR7) - RPB950Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Toll Like Receptor 7 (TLR7) - RPB950Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Toll Like Receptor 7 (TLR7) - RPB950Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Human Toll-like receptor 7(TLR7) ,partial - CSB-YP023606HU CSB-EP023606HU CSB-BP023606HU CSB-MP023606HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TLR7, Peptide - MBS658836 from MyBioSource Category Peptide Prices $280.00 Sizes 50 µg

TLR7 Recombinant Protein Antigen - NBP2-32483PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TLR7-Antibody-C-term-Blocking-Peptide - BP1507a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TLR7 Peptide, Human - M34GP16006H from Creative Peptides Category Peptide Source Synthetic. Species Human

TLR7 Recombinant Protein (OPCD07507) - OPCD07507 from Aviva Systems Biology Category Protein Source E.coli Species Human

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