Gene Symbol | FCN3 |
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Entrez Gene | 8547 |
Alt Symbol | FCNH, HAKA1 |
Species | Human |
Gene Type | protein-coding |
Description | ficolin (collagen/fibrinogen domain containing) 3 |
Other Description | H-ficolin|collagen/fibrinogen domain-containing lectin 3 p35|collagen/fibrinogen domain-containing protein 3|ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)|ficolin 3|ficolin-3 |
Swissprots | O75636 Q8WW86 Q6IBJ5 |
Accessions | AAU85296 CAF86408 EAX07756 EAX07757 O75636 AK075140 BAC11429 AK309540 AK309576 AY358081 AAQ88448 AY358283 AAQ88650 BC020731 AAH20731 CR456808 CAG33089 DQ892028 ABM82954 DQ895220 ABM86146 XM_011542339 XP_011540641 NM_003665 NP_003656 NM_173452 NP_775628 |
Function | May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota. {ECO:0000269|PubMed:11907111}. |
Subcellular Location | Secreted. Note=Found in blood plasma, bronchus, alveolus and bile duct. |
Tissue Specificity | Liver and lung. In liver it is produced by bile duct epithelial cells and hepatocytes. In lung it is produced by both ciliated bronchial epithelial cells and type II alveolar epithelial cells. {ECO:0000269|PubMed:10330454}. |
H-ficolin (G-15) - sc-55202 from Santa Cruz Biotechnology
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H-ficolin (H-55) - sc-134912 from Santa Cruz Biotechnology
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H-ficolin (S-19) - sc-55204 from Santa Cruz Biotechnology
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Anti-FCN3 antibody - ab76474 from Abcam
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Anti-FCN3 antibody - ab112943 from Abcam
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Anti-FCN3 antibody - ab98136 from Abcam
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Anti-FCN3 / Ficolin-3 Antibody (aa214-243) - LS-C166110 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa213-243, APC) - LS-C235263 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa213-243, AP) - LS-C235264 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa213-243, Biotin) - LS-C235265 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa213-243, PE) - LS-C235268 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa213-243, FITC) - LS-C235266 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa213-243, Azide-free, HRP) - LS-C249983 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa34-297, FITC) - LS-C302583 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa34-297, Biotin) - LS-C298091 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody - LS-C310350 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa35-84) - LS-C107622 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa34-297) - LS-C293942 from LifeSpan Bioscience
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Anti-FCN3 / Ficolin-3 Antibody (aa213-243) - LS-C329546 from LifeSpan Bioscience
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Ficolin-3 Isoform 2 Antibody (296134) - MAB2367 from Novus Biologicals
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Ficolin-3 Isoform 2 Antibody [Unconjugated] - AF2367 from Novus Biologicals
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Ficolin-3 Antibody - NBP1-58024 from Novus Biologicals
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Ficolin-3 Antibody - H00008547-D01P from Novus Biologicals
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Ficolin-3 Antibody - H00008547-B01 from Novus Biologicals
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Ficolin-3 Antibody - H00008547-A01 from Novus Biologicals
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