Gene Symbol | INSL3 |
---|---|
Entrez Gene | 3640 |
Alt Symbol | RLF, RLNL, ley-I-L |
Species | Human |
Gene Type | protein-coding |
Description | insulin-like 3 (Leydig cell) |
Other Description | insulin-like 3|leydig insulin -like hormone|leydig insulin-like peptide|prepro-INSL3|relaxin-like factor b |
Swissprots | Q3KPI5 G3XAG0 Q3KPI6 Q9UPH6 Q9UEA2 B4DZ72 P51460 Q6YNB5 |
Accessions | AAD22740 CAA52017 CBH19326 EAW84633 EAW84634 EAW84635 EAW84636 P51460 AK302780 BAG63984 AY082014 AAL92559 BC032810 AAH32810 BC040435 BC053345 AAH53345 BC061886 BC071706 AAH71706 BC106721 AAI06722 BC106722 AAI06723 BC107045 BX334591 S72482 AAB31371 NM_001265587 NP_001252516 NM_005543 NP_005534 |
Function | Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in prenatal and postnatal Leydig cells. Found as well in the corpus luteum, trophoblast, fetal membranes and breast. {ECO:0000269|PubMed:7852540}. |