INSL3

Gene Symbol INSL3
Entrez Gene 3640
Alt Symbol RLF, RLNL, ley-I-L
Species Human
Gene Type protein-coding
Description insulin-like 3 (Leydig cell)
Other Description insulin-like 3|leydig insulin -like hormone|leydig insulin-like peptide|prepro-INSL3|relaxin-like factor b
Swissprots Q3KPI5 G3XAG0 Q3KPI6 Q9UPH6 Q9UEA2 B4DZ72 P51460 Q6YNB5
Accessions AAD22740 CAA52017 CBH19326 EAW84633 EAW84634 EAW84635 EAW84636 P51460 AK302780 BAG63984 AY082014 AAL92559 BC032810 AAH32810 BC040435 BC053345 AAH53345 BC061886 BC071706 AAH71706 BC106721 AAI06722 BC106722 AAI06723 BC107045 BX334591 S72482 AAB31371 NM_001265587 NP_001252516 NM_005543 NP_005534
Function Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
Subcellular Location Secreted.
Tissue Specificity Expressed in prenatal and postnatal Leydig cells. Found as well in the corpus luteum, trophoblast, fetal membranes and breast. {ECO:0000269|PubMed:7852540}.

INSL3 (FL-131) - sc-134586 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

INSL3 (K-12) - sc-48550 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-INSL3 antibody - ab65981 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human testicle staining INSL3 in cytoplasm using ab65981 at 2µg/ml. DAB chromogenic reaction.

Anti-INSL3 antibody - ab118422 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-INSL3 antibody (ab118422) at 1/500 dilution + Human placenta lysate

Anti-INSL3 antibody - ab193444 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INSL3 antibody [EPR14834(2)] - ab199536 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14834(2)
All lanes : Anti-INSL3 antibody [EPR14834(2)] (ab199536) at 1/5000 dilutionLane 1 : Mouse testis lysateLane 2 : Human testis lysateLane 3 : Human fetal heart lysateLane 4 : Human fetal kidney lysateLane 5 : Human fetal spleen lysateLane 6 : NCCIT (Human pluripotent embryonal carcinoma) whole cell lysateLane 7 : A431 (Human epidermoid carcinoma) whole cell lysateLane 8 : Jurkat (Human T cell leukemia cells from peripheral blood) whole cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-INSL3 Antibody (N-Terminus) - LS-C121985 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody (aa36-52) - LS-C121986 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody (C-Terminus) - LS-C144858 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody (aa115-131, Magnetic beads) - LS-C171759 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody (Biotin) - LS-C183927 from LifeSpan Bioscience

Prices $800.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody (CF) - LS-C183928 from LifeSpan Bioscience

Prices $800.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody (Rhodamine) - LS-C183929 from LifeSpan Bioscience

Prices $800.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody - LS-C190935 from LifeSpan Bioscience

Prices $740.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody - LS-C190936 from LifeSpan Bioscience

Prices $740.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody (aa115-131) - LS-C171758 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody - LS-C341829 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody (aa29-128) - LS-C178620 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INSL3 Antibody - LS-C334244 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of U937 cell line, using INSL3 antibody.

Anti-INSL3 Antibody (aa19-68) IHC-plus™ - LS-B11421 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-INSL3 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11421 concentration 20 ug/ml.

INSL3 Antibody - NBP1-18706 from Novus Biologicals

Prices $329.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

RLF Antibody - NBP1-33086 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RLF Antibody [NBP1-33086] - Sample (30 ug of whole cell lysate)A: Raji 7. 5% SDS PAGE, antibody diluted at 1:500.

INSL3 Antibody - NBP1-81223 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

INSL3 Polyclonal Antibody - bs-11301R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

INSL3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11301R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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