CTGF

Gene Symbol CTGF
Entrez Gene 1490
Alt Symbol CCN2, HCS24, IGFBP8, NOV2
Species Human
Gene Type protein-coding
Description connective tissue growth factor
Other Description CCN family member 2|IBP-8|IGF-binding protein 8|IGFBP-8|hypertrophic chondrocyte-specific protein 24|insulin-like growth factor-binding protein 8
Swissprots Q6LCY0 Q96A79 P29279 Q96QX2 Q9UDL6 E1P578
Accessions AAK60505 AAK60506 AAK60507 AAZ29611 ADL14512 CAA63267 CAS92743 CBX51740 EAW48038 EAW48039 P29279 AF127918 AK092280 BAG52518 AK125220 BAG54167 AK290884 BAF83573 AK315207 BAG37644 AY395801 AAQ95223 AY550024 AAS55639 BC087839 AAH87839 BT019794 AAV38597 BT019795 AAV38598 CR541734 CAG46534 CR541759 CAG46559 DA552292 M92934 AAA91279 U14750 AAA75378 X78947 CAA55544 NM_001901 NP_001892
Function Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. {ECO:0000269|PubMed:10614647, ECO:0000269|PubMed:12553878}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250}. Secreted {ECO:0000250}.
Tissue Specificity Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. {ECO:0000269|PubMed:1756408}.
Top Pathways Hippo signaling pathway

CTGF (E-5) - sc-365970 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CTGF (E-5): sc-365970. Western blot analysis of CTGF expression in non-transfected: sc-117752 (A) and human CTGF transfected: sc-111612 (B) 293T whole cell lysates.

CTGF (G-14) - sc-34772 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CTGF (G-14): sc-34772. Western blot analysis of CTGF expression in mouse heart tissue extract.

CTGF (C-19) - sc-14940 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CTGF (C-19): sc-14940. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of Gobblet cells.

CTGF (B-6) - sc-373936 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CTGF (B-6): sc-373936. Western blot analysis of CTGF expression in non-transfected: sc-117752 (A) and human CTGF transfected: sc-111612 (B) 293T whole cell lysates.

CTGF (H-55) - sc-25440 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CTGF (H-55): sc-25440. Western blot analysis of CTGF expression in HeLa whole cell lysate.

CTGF (D-13) - sc-34771 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CTGF (L-20) - sc-14939 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CTGF (L-20): sc-14939. Immunoperoxidase staining of formalin fixed, paraffin-embedded human endometrial cancer tissue showing cytoplasmic staining of tumor cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

CTGF (6B13) - sc-101586 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CTGF (6B13): sc-101586. Western blot analysis of CTGF expression in non-transfected: sc-117752 (A) and mouse CTGF transfected: sc-119498 (B) 293T whole cell lysates.

Anti-CTGF antibody - ab6992 from Abcam

Prices $400.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab6992 staining GTGF (green) in Human vasculature tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with mathacarn and blocked with 10% serum for 20 minutes at 25°C. Samples were incubated with primary antibody (1/400) for 14 hours at 4°C. An Alexa Fluor® 488-conjugated Goat anti-rabbit IgG polyclonal (1/400) was used as the secondary antibody. Blue - DAPI Nuclei.See Abreview

Anti-CTGF antibody - ab5097 from Abcam

Prices $391.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab5097 staining CTGF in human heart tissue section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Tissue underwent fixation in formaldehyde, heat mediated antigen retrieval in buffer and blocking (5 minutes/peroxidase block then 10 minutes/protein block) for 15 minutes at 20°C. The primary antibody was diluted, 1/50 and incubated with sample for 45 minutes at 20°C. A HRP conjugated goat polyclonal to rabbit IgG was used undiluted as secondary.See Abreview

Anti-CTGF antibody - ab109606 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CTGF antibody [17-73-F1] - ab94939 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 17-73-F1
Anti-CTGF antibody [17-73-F1] (ab94939) at 10 µg/ml + CTGF Recombinant Protein (Human) at 0.1 µgSecondaryGoat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CTGF antibody [17-73-F1] - BSA and Azide free - ab174607 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 17-73-F1

Anti-CTGF antibody [558CT34.4.4] - ab178510 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 558CT34.4.4
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human Lung, Respiratory Epithelium tissue labeling CTGF with ab178510 at 1/50 dilution.

Anti-CTGF antibody (Biotin) - ab84244 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CTGF antibody - C-terminal - ab135812 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CTGF antibody - C-terminal (ab135812) at 1/50 dilution + NCI-H460 cell line lysates at 35 µg

Anti-CTGF antibody - Carboxyterminal end - ab59681 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CTGF antibody - Carboxyterminal end (ab59681) at 0.5 µg/mlLane 1 : recombinant human CTGF at 1 µgLane 2 : recombinant human CTGF at 0.25 µgLane 3 : recombinant human CTGF at 0.05 µgLane 4 : recombinant human CTGF at 0.01 µg

Anti-CTGF Antibody - LS-C159416 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
CTGF Antibody western blot of A549 cell line lysates (35 ug/lane). The CTGF antibody detected the CTGF protein (arrow).

Anti-CTGF Antibody (clone 558CT34.4.4, Azide-free, HRP) - LS-C206980 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 558CT34.4.4

Anti-CTGF Antibody (clone 558CT34.4.4, PE) - LS-C206322 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 558CT34.4.4

Anti-CTGF Antibody (aa165-193, FITC) - LS-C208697 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTGF Antibody (aa165-193, APC) - LS-C208696 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTGF Antibody (aa165-193, PE) - LS-C208698 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTGF Antibody (aa165-193, AP) - LS-C208695 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTGF Antibody - LS-C285691 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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