Gene Symbol | CTGF |
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Entrez Gene | 1490 |
Alt Symbol | CCN2, HCS24, IGFBP8, NOV2 |
Species | Human |
Gene Type | protein-coding |
Description | connective tissue growth factor |
Other Description | CCN family member 2|IBP-8|IGF-binding protein 8|IGFBP-8|hypertrophic chondrocyte-specific protein 24|insulin-like growth factor-binding protein 8 |
Swissprots | Q6LCY0 Q96A79 P29279 Q96QX2 Q9UDL6 E1P578 |
Accessions | AAK60505 AAK60506 AAK60507 AAZ29611 ADL14512 CAA63267 CAS92743 CBX51740 EAW48038 EAW48039 P29279 AF127918 AK092280 BAG52518 AK125220 BAG54167 AK290884 BAF83573 AK315207 BAG37644 AY395801 AAQ95223 AY550024 AAS55639 BC087839 AAH87839 BT019794 AAV38597 BT019795 AAV38598 CR541734 CAG46534 CR541759 CAG46559 DA552292 M92934 AAA91279 U14750 AAA75378 X78947 CAA55544 NM_001901 NP_001892 |
Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. {ECO:0000269|PubMed:10614647, ECO:0000269|PubMed:12553878}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. Secreted {ECO:0000250}. |
Tissue Specificity | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. {ECO:0000269|PubMed:1756408}. |
Top Pathways | Hippo signaling pathway |
Active human CTGF protein fragment - ab50044 from Abcam
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CTGF protein fragment - ab7861 from Abcam
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Human CTGF full length protein - ab203539 from Abcam
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Human CTGF full length protein - ab202161 from Abcam
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Human CTGF peptide - ab13741 from Abcam
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Human CTGF protein fragment - ab131749 from Abcam
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Human CTGF protein fragment - ab69786 from Abcam
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CTGF Antibody Blocking Peptide - LS-E2410 from LifeSpan Bioscience
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CTGF Antibody Blocking Peptide - LS-E9254 from LifeSpan Bioscience
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CTGF/CCN2 Blocking Peptide - NB100-724PEP from Novus Biologicals
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Recombinant Human CTGF/CCN2 Protein - NBP1-91182 from Novus Biologicals
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CTGF/CCN2 Recombinant Protein - H00001490-P01 from Novus Biologicals
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CTGF/CCN2 Recombinant Protein - P4578 from Novus Biologicals
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Recombinant Human CTGF/CCN2 Protein - NBP1-99873 from Novus Biologicals
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CTGF/CCN2 Protein - NBP1-99944 from Novus Biologicals
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CTGF/CCN2 Protein - NBP1-43178 from Novus Biologicals
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CTGF-Antibody-Center-Blocking-peptide - BP13399c from Abgent, a WuXi AppTec company
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CTGF-Antibody-C-term-Blocking-Peptide - BP7778b from Abgent, a WuXi AppTec company
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CTGF recombinant protein - GTX65064 from GeneTex
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CTGF Recombinant Protein (Active) - GTX48458-PRO from GeneTex
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Recombinant human Connective tissue growth factor protein (OPCA00818) - OPCA00818 from Aviva Systems Biology
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Recombinant human Connective tissue growth factor protein (OPCA00819) - OPCA00819 from Aviva Systems Biology
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CTGF Protein (OPPA00697) - OPPA00697 from Aviva Systems Biology
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CTGF Protein (OPPA01507) - OPPA01507 from Aviva Systems Biology
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CTGF Protein (OPPA01616) - OPPA01616 from Aviva Systems Biology
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