Gene Symbol | CTGF |
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Entrez Gene | 1490 |
Alt Symbol | CCN2, HCS24, IGFBP8, NOV2 |
Species | Human |
Gene Type | protein-coding |
Description | connective tissue growth factor |
Other Description | CCN family member 2|IBP-8|IGF-binding protein 8|IGFBP-8|hypertrophic chondrocyte-specific protein 24|insulin-like growth factor-binding protein 8 |
Swissprots | Q6LCY0 Q96A79 P29279 Q96QX2 Q9UDL6 E1P578 |
Accessions | AAK60505 AAK60506 AAK60507 AAZ29611 ADL14512 CAA63267 CAS92743 CBX51740 EAW48038 EAW48039 P29279 AF127918 AK092280 BAG52518 AK125220 BAG54167 AK290884 BAF83573 AK315207 BAG37644 AY395801 AAQ95223 AY550024 AAS55639 BC087839 AAH87839 BT019794 AAV38597 BT019795 AAV38598 CR541734 CAG46534 CR541759 CAG46559 DA552292 M92934 AAA91279 U14750 AAA75378 X78947 CAA55544 NM_001901 NP_001892 |
Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. {ECO:0000269|PubMed:10614647, ECO:0000269|PubMed:12553878}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. Secreted {ECO:0000250}. |
Tissue Specificity | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. {ECO:0000269|PubMed:1756408}. |
Top Pathways | Hippo signaling pathway |
SimpleChIP ® Human CTGF Upstream Primers - 14928 from Cell Signaling Technology
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SimpleChIP ® Human CTGF Promoter Primers - 14927 from Cell Signaling Technology
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Mouse CTGF ELISA Kit (Sandwich ELISA) - LS-F5553 from LifeSpan Bioscience
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Rat CTGF ELISA Kit (Sandwich ELISA) - LS-F5552 from LifeSpan Bioscience
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Human CTGF ELISA Kit (Sandwich ELISA) - LS-F5551 from LifeSpan Bioscience
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Pig CTGF ELISA Kit (Sandwich ELISA) - LS-F6225 from LifeSpan Bioscience
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Rabbit CTGF ELISA Kit (Sandwich ELISA) - LS-F6226 from LifeSpan Bioscience
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Human CTGF ELISA Kit (Sandwich ELISA) - LS-F557 from LifeSpan Bioscience
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Rat CTGF ELISA Kit (Sandwich ELISA) - LS-F11239 from LifeSpan Bioscience
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Mouse CTGF ELISA Kit (Sandwich ELISA) - LS-F11238 from LifeSpan Bioscience
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Human CTGF ELISA Kit (Competitive EIA) - LS-F11237 from LifeSpan Bioscience
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CTGF ELISA Kit (Human) : 96 Wells (OKAG00010) - OKAG00010 from Aviva Systems Biology
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Human CTGF ELISA Kit - abx151200 from Abbexa
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Connective tissue growth factor (CTGF), Human, ELISA Kit - CSB-E07875h from ARP American Research Products
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Connective Tissue Growth Factor (CTGF), Human, ELISA Kit - SEA010Hu from ARP American Research Products
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Connective tissue growth factor, CTGF, Human, ELISA Kit - E0010h from ARP American Research Products
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Connective Tissue Growth Factor, Human, ELISA Kit - E01C0563 from ARP American Research Products
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Connective Tissue Growth Factor, CTGF, Human, ELISA Kit - E-EL-H0828 from ARP American Research Products
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Connective Tissue Growth Factor, CTGF, Mouse, ELISA Kit - E-EL-M0340 from ARP American Research Products
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Connective Tissue Growth Factor, CTGF, Rat, ELISA Kit - E-EL-R0259 from ARP American Research Products
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Connective Tissue Growth Factor, CTGF, Rabbit, ELISA Kit - E-EL-RB1819 from ARP American Research Products
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Connective Tissue Growth Factor, CTGF, Chicken, ELISA Kit - E-EL-Ch0700 from ARP American Research Products
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Connective Tissue Growth Factor, CTGF, Porcine, ELISA Kit - E-EL-P1264 from ARP American Research Products
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Connective Tissue Growth Factor, CTGF, Guinea Pig, ELISA Kit - E-EL-GP0051 from ARP American Research Products
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Connective Tissue Growth Factor, CTGF, Monkey, ELISA Kit - E-EL-MK0180 from ARP American Research Products
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