AGO1

Gene Symbol AGO1
Entrez Gene 26523
Alt Symbol EIF2C, EIF2C1, GERP95, Q99
Species Human
Gene Type protein-coding
Description argonaute RISC catalytic component 1
Other Description Golgi Endoplasmic Reticulum protein 95 kDa|argonaute 1|argonaute1|eIF-2C 1|eIF2C 1|eukaryotic translation initiation factor 2C, 1|hAgo1|protein argonaute-1|putative RNA-binding protein Q99
Swissprots Q9UL18 Q5TA57 Q6P4S0
Accessions EAX07396 Q9UL18 AF093097 AAF00068 AK000326 AK001622 BAG50952 AK002003 AK025726 AK027611 AK125879 AK314148 BAG36835 BC063275 AAH63275 CR936823 U92986 XM_011541236 XP_011539538 XM_011541237 XP_011539539 XM_011541238 XP_011539540 XM_011541239 XP_011539541 NM_012199 NP_036331
Function Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs). {ECO:0000269|PubMed:16289642, ECO:0000269|PubMed:16936728, ECO:0000269|PubMed:18771919}.
Subcellular Location Cytoplasm, P-body {ECO:0000269|PubMed:16289642, ECO:0000269|PubMed:20616046}.

eIF2C CRISPR/Cas9 KO Plasmid (h) - sc-409888 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C HDR Plasmid (h) - sc-409888-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C Double Nickase Plasmid (h) - sc-409888-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C Double Nickase Plasmid (h2) - sc-409888-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C CRISPR Activation Plasmid (h) - sc-409888-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C CRISPR Activation Plasmid (h2) - sc-409888-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C Lentiviral Activation Particles (h) - sc-409888-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C Lentiviral Activation Particles (h2) - sc-409888-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C1 siRNA (h) - sc-44408 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eIF2C1 shRNA Plasmid (h) - sc-44408-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eIF2C1 shRNA (h) Lentiviral Particles - sc-44408-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AGO1/EIF2C1 RNAi - H00026523-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU042781 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7749 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7749 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AGO1 siRNA (Human) - CRH8847 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGO1 - MBS8217720 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EIF2C1 (NM_012199.2) - SHH284313 from Creative biogene

Category siRNA
Species Reactivities Human

AGO1 shRNA Plasmid (Human) - CHH8847 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EIF2C1 miRNA 3'UTR clone - MiUTR1H-03159 from Creative biogene

Species Reactivities Human
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