S1PR3

Gene Symbol S1PR3
Entrez Gene 1903
Alt Symbol EDG-3, EDG3, LPB3, S1P3
Species Human
Gene Type protein-coding
Description sphingosine-1-phosphate receptor 3
Other Description G protein-coupled receptor, endothelial differentiation gene-3|S1P receptor 3|S1P receptor EDG3|S1P receptor Edg-3|endothelial differentiation G-protein coupled receptor 3|endothelial differentiation, sphingolipid G-protein-coupled receptor, 3|sphingosine 1-phosphate receptor 3|sphingosine 1-phosphate receptor Edg-3
Swissprots Q99500 Q5SQD8 Q7Z5I2
Accessions AAP84353 CAA58744 EAW62758 Q99500 AF022139 AAC51906 AK312798 BAG35658 AL832194 BC060827 AAH60827 BC069579 AAH69579 BM990167 DA722994 DR763542 NM_005226 NP_005217
Function Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. {ECO:0000269|PubMed:10617617}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.
Top Pathways Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

EDG-3 (V-20) - sc-16076 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EDG-3 (V-20): sc-16076. Immunofluorescence staining of methanol-fixed Hep G2 cells showing membrane localization.

EDG-3 (M-17) - sc-22214 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EDG-3 (M-17): sc-22214. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.

EDG-3 (H-70) - sc-30024 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
EDG-3 (H-70): sc-30024. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin cancer tissue showing membrane staining of tumor cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

EDG-3 (H-15) - sc-22210 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EDG-3 (H-15): sc-22210. Immunofluorescence staining of methanol-fixed Hep G2 cells showing membrane localization.

EDG-3 (G-17) - sc-22211 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EDG-3 (G-17): sc-22211. Immunofluorescence staining of methanol-fixed Hep G2 cells showing membrane localization.

Anti-EDG3 antibody - ab74477 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EDG3 antibody (ab74477) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : U-87 MG (Human glioblastoma astrocytoma) Whole Cell Lysate Lane 3 : SW480 (Human colon adenocarcinoma cell line) Whole Cell Lysate Lane 4 : Caco 2 (Human colonic carcinoma cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-EDG3 antibody - ab115463 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115463 at 10 &microg/ml staining EDG3 in Formalin-fixed, Paraffin-embedded Human kidney tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-EDG3 antibody - ab134239 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-EDG3 antibody (ab134239) at 1 µg/ml + HeLa cell lysate at 10 µg

Anti-EDG3 antibody - ab186039 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human kidney tissue labeling EDG3 with ab186039 at 4 µg/ml.

Anti-EDG3 antibody [AS61] - ab12254 from Abcam

Prices $370.00
Sizes 25 µg
Host Mouse
Clonality Monoclonal
Clone AS61

Anti-EDG3 antibody [EPR4540(2)] - ab108370 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4540(2)
All lanes : Anti-EDG3 antibody [EPR4540(2)] (ab108370) at 1/10000 dilutionLane 1 : MCF-7 cell lysateLane 2 : HepG2 cell lysateLane 3 : 293T cell lysateLane 4 : JAR cell lysateLysates/proteins at 10 µg per lane.

Anti-EDG3 antibody [EPR4541(2)] - ab126622 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4541(2)
All lanes : Anti-EDG3 antibody [EPR4541(2)] (ab126622) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : Human heart tissue lysateLane 3 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilution

Anti-EDG3 antibody [MM0899-64S4] - ab201671 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0899-64S4

Anti-EDG3 antibody - Aminoterminal end - ab38324 from Abcam

Prices $382.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-EDG3 antibody - Aminoterminal end (ab38324) at 1/100 dilution + mouse kidney lysate

Anti-EDG3 antibody - C-terminal - ab188601 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin-Fixed, Paraffin-Embedded Human kidney tissue labeling EDG3 with ab188601 at 20 µg/ml.

Anti-EDG3 antibody - C-terminal - ab153735 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-EDG3 antibody - C-terminal (ab153735) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-EDG3 antibody - N-terminal - ab150573 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed and paraffin embedded Human heart tissue labeling EDG3 using ab150573 at 5ug/ml.

Anti-SIPR3 / EDG3 / S1P3 Antibody (N-Terminus) IHC-plus™ - LS-A1752 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EDG3 / S1P3 antibody LS-A1752 IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-SIPR3 / EDG3 / S1P3 Antibody (C-Terminus) IHC-plus™ - LS-A1031 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EDG3 / S1P3 antibody LS-A1031 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-SIPR3 / EDG3 / S1P3 Antibody (C-Terminus) - LS-C26477 from LifeSpan Bioscience

Prices $570.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SIPR3 / EDG3 / S1P3 Antibody - LS-C26781 from LifeSpan Bioscience

Prices $570.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SIPR3 / EDG3 / S1P3 Antibody - LS-C26782 from LifeSpan Bioscience

Prices $570.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SIPR3 / EDG3 / S1P3 Antibody - LS-C96206 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SIPR3 / EDG3 / S1P3 Antibody (aa1-378) - LS-C132175 from LifeSpan Bioscience

Prices $445.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-SIPR3 / EDG3 / S1P3 Antibody - LS-C26774 from LifeSpan Bioscience

Prices $570.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of EDG4/LPA2 (NT) antibody at 5 ug/ml on RH7777 cells transfected with EDG4/LPA2 protein in the absence (1) and presence (2) of blocking peptide.
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