Gene Symbol | ST3GAL6 |
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Entrez Gene | 10402 |
Alt Symbol | SIAT10, ST3GALVI |
Species | Human |
Gene Type | protein-coding |
Description | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
Other Description | CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI|alpha2,3-sialyltransferase ST3Gal VI|sialyltransferase 10 (alpha-2,3-sialyltransferase VI)|type 2 lactosamine alpha-2,3-sialyltransferase |
Swissprots | F8W6U0 D3DN39 B2RCH2 Q9Y274 B3KMI1 |
Accessions | CAS91693 CBX32761 CBX46694 EAW79849 EAW79850 EAW79851 EAW79852 EAW79853 Q9Y274 AB022918 BAA77609 AF119391 AAD39131 AK001922 BAG50993 AK315111 BAG37569 AL539506 BC001266 BC012092 BC023312 AAH23312 CB960395 DB036799 HY123342 XM_005247067 XP_005247124 XM_005247069 XP_005247126 XM_005247070 XP_005247127 XM_005247071 XP_005247128 XM_005247072 XP_005247129 XM_006713474 XP_006713537 XM_006713476 XP_006713539 XM_011512335 XP_011510637 XM_011512336 XP_011510638 NM_001271142 NP_001258071 NM_001271145 NP_001258074 NM_001271146 NP_001258075 NM_001271147 NP_001258076 NM_001271148 NP_001258077 NM_006100 NP_006091 |
Function | Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Glycosphingolipid biosynthesis - lacto and neolacto series |
Sialyltransferase 10 (C-20) - sc-68738 from Santa Cruz Biotechnology
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Anti-ST3GAL6 antibody - ab106527 from Abcam
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Anti-ST3GAL6 antibody - ab103643 from Abcam
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Anti-ST3GAL6 Antibody (C-Terminus) - LS-C108518 from LifeSpan Bioscience
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ST3GAL6 Antibody - NBP1-92446 from Novus Biologicals
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ST3GAL6 Antibody - NBP1-77353 from Novus Biologicals
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Anti-ST3GAL6 antibody produced in rabbit - SAB3500045 from Sigma-Aldrich
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ST3gal6 antibody - orb75202 from Biorbyt
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ST3GAL6 antibody - 70R-20550 from Fitzgerald
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ST3GAL6 antibody - 13154-1-AP from Acris Antibodies
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ST3GAL6 antibody - AP30830PU-N from Acris Antibodies
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ST3gal6 Antibody - 5169 from ProSci
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ST3GAL6 antibody - 13154-1-AP from Proteintech Group
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BAFF, Polyclonal Antibody - MBS691109 from MyBioSource
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BAFF, Monoclonal Antibody - MBS690156 from MyBioSource
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ST3gal6 Antibody - 254072 from ABBIOTEC
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ST3gal6 Antibody - 24896 from Signalway Antibody
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Anti-ST3GAL6 (C-terminal) polyclonal antibody - DPAB-L21193 from Creative Diagnostics
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Anti-ST3GAL6 monoclonal antibody - DCABH-13614 from Creative Diagnostics
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ST3GAL6 Polyclonal Antibody - PA5-20748 from Thermo Fisher Scientific
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ST3 beta-galactoside alpha-2, 3-sialyltransferase 6 , Polyclonal Antibody - MBS716546 from MyBioSource
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ST3gal6, Polyclonal Antibody - MBS150396 from MyBioSource
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ST3gal6 Antibody - 600-401-EV2 from Rockland Immunochemicals Inc
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ST3gal6 Antibody (OAPB00889) - OAPB00889 from Aviva Systems Biology
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ST3gal6, Polyclonal Antibody - MBS9400835 from MyBioSource
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