Gene Symbol | ST3GAL6 |
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Entrez Gene | 10402 |
Alt Symbol | SIAT10, ST3GALVI |
Species | Human |
Gene Type | protein-coding |
Description | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
Other Description | CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI|alpha2,3-sialyltransferase ST3Gal VI|sialyltransferase 10 (alpha-2,3-sialyltransferase VI)|type 2 lactosamine alpha-2,3-sialyltransferase |
Swissprots | F8W6U0 D3DN39 B2RCH2 Q9Y274 B3KMI1 |
Accessions | CAS91693 CBX32761 CBX46694 EAW79849 EAW79850 EAW79851 EAW79852 EAW79853 Q9Y274 AB022918 BAA77609 AF119391 AAD39131 AK001922 BAG50993 AK315111 BAG37569 AL539506 BC001266 BC012092 BC023312 AAH23312 CB960395 DB036799 HY123342 XM_005247067 XP_005247124 XM_005247069 XP_005247126 XM_005247070 XP_005247127 XM_005247071 XP_005247128 XM_005247072 XP_005247129 XM_006713474 XP_006713537 XM_006713476 XP_006713539 XM_011512335 XP_011510637 XM_011512336 XP_011510638 NM_001271142 NP_001258071 NM_001271145 NP_001258074 NM_001271146 NP_001258075 NM_001271147 NP_001258076 NM_001271148 NP_001258077 NM_006100 NP_006091 |
Function | Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Glycosphingolipid biosynthesis - lacto and neolacto series |
Human ST3GAL6 protein fragment - ab160973 from Abcam
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ST3GAL6 Antibody Blocking Peptide - LS-E30704 from LifeSpan Bioscience
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Recombinant Human ST3GAL6 Protein - H00010402-Q01 from Novus Biologicals
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ST3GAL6 Peptide - NBP1-77353PEP from Novus Biologicals
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ST3gal6 Peptide - GTX85283-PEP from GeneTex
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ST3GAL6 - H00010402-Q01 from Acris Antibodies
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ST3GAL6 - H00010402-Q01-10 from Acris Antibodies
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ST3GAL6 - H00010402-Q01-25 from Acris Antibodies
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ST3GAL6 Control Peptide - AP30830CP-N from Acris Antibodies
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ST3gal6 Peptide - 5169P from ProSci
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ST3GAL6 fusion protein - ag14399 from Proteintech Group
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ST3GAL6 fusion protein - Ag3782 from Proteintech Group
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ST3GAL6 - TP305750 from Acris Antibodies
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ST3GAL6 Protein - NBP1-92446PEP from Novus Biologicals
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SIA10-Antibody-C-term-Blocking-Peptide - BP5077b from Abgent, a WuXi AppTec company
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ST3GAL6 Peptide, Human - M34GP15238H from Creative Peptides
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BAFF, Recombinant Protein - MBS691863 from MyBioSource
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