KAT5

Gene Symbol	KAT5
Entrez Gene	10524
Alt Symbol	ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, ZC2HC5, cPLA2
Species	Human
Gene Type	protein-coding
Description	K(lysine) acetyltransferase 5
Other Description	60 kDa Tat-interactive protein|HIV-1 Tat interactive protein, 60kDa|K-acetyltransferase 5|Tat interacting protein, 60kDa|cPLA(2)-interacting protein|cPLA2 interacting protein|histone acetyltransferase HTATIP|histone acetyltransferase KAT5
Swissprots	Q92993 Q9BWK7 C9JL99 O95624 Q13430 Q6GSE8 Q561W3 B4E3C7 Q17RW5
Accessions	AAO21130 EAW74427 EAW74428 EAW74429 EAW74430 EAW74431 EAW74432 Q92993 AB209813 BAD93050 AK130717 AK225100 AK226002 AK304664 BAG65439 AK313297 BAG36104 BC000166 AAH00166 BC013211 BC064912 AAH64912 BC093032 AAH93032 BC117167 AAI17168 BC143290 BC143296 AAI43297 BG720537 BI463394 BU737532 DA043042 DB003934 DB103287 HQ258620 ADR83372 U40989 AAB02683 U67734 AAD00163 U74667 AAB18236 XM_006718421 XP_006718484 XM_011544733 XP_011543035 NM_001206833 NP_001193762 NM_006388 NP_006379 NM_182709 NP_874368 NM_182710 NP_874369
Function	Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation. Relieves NR1D2-mediated
Subcellular Location	Nucleus {ECO:0000269|PubMed:17360565}. Nucleus, nucleolus. Cytoplasm, perinuclear region. Note=Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region and UV irradiation induces translocation into punctuate subnuclear structures named nuclear bodies.
Top Pathways	HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat KAT5 / TIP60 ELISA Kit (Cell-Based ELISA) - LS-F2356 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.5-10 ng/ml

Mouse/Human Phospho-KAT5 / TIP60 (Ser86) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1311 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.5-10 ng/ml

Phospholipase A2, Cytosolic, cPLA2, Mouse, ELISA Kit - E-EL-M1347 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Human Cpla2 ELISA Kit - HC0821 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine Cpla2 ELISA Kit - AC0821 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

K (lysine) acetyltransferase 5, ELISA Kit - MBS9316082 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

K-Acetyltransferase 5 (KAT5), ELISA Kit - MBS9311809 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml Range 0.625ng/ml-20ng/ml

TIP60 Colorimetric Cell-Based ELISA Kit - CB5694 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

TIP60 (Phospho-Ser86) Colorimetric Cell-Based ELISA Kit - CBP1316 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Human cPLA2(Cytosolic Phospholipase A2) ELISA Kit - E-EL-H1064 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human cPLA2 (Cytosolic Phospholipase A2) CLIA Kit - E-CL-H0715 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

Human Cytosolic Phospholipase A2 ELISA - E01C0814 from BlueGene Biotech Category ELISA Kit

Human cPLA2(Cytosolic Phospholipase A2) ELISA Kit - E-EL-H1064 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mLng/mL Range 0.16~10 ng/mL

Human cPLA2 (Cytosolic Phospholipase A2) CLIA Kit - E-CL-H0715 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156-10ng/mL

TIP60 ELISA Kit - DEIA-XYA1763 from Creative Diagnostics Category ELISA Kit

TIP60 (Phospho-Ser86) ELISA Kit - DEIA-XYA1764 from Creative Diagnostics Category ELISA Kit

Mouse KAT5 / TIP60 ELISA Kit (Competitive EIA) - LS-F28296 from LifeSpan Bioscience Category ELISA Kit Prices $870.00 Sizes 1 plate Sensitivity 0.1 ng/ml Range 0.5-10 ng/ml

Human Cpla2 ELISA Kit - E011269 from Biobool Category ELISA Kit

Human KAT5 ELISA Kit - E021229 from Biobool Category ELISA Kit

Human Cpla2 ELISA Kit - EHC0821 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

anti-TIP60 antibody - ARG65853 from Arigo Biolaboratories Category ELISA Kit

Human KAT5 / TIP60 ELISA Kit (Competitive EIA) - LS-F39574 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.39 Range 0.5-10 ng/ml

Human cPLA2 (Cytosolic Phospholipase A2) ELISA Kit - EKE60665 from Biomatik Category ELISA Kit Prices $609.00 Sizes 96 tests Sensitivity 0.1 ng/mL Range 0.16-10 ng/mL

TIP60 Colorimetric Cell-Based ELISA Kit - EKA50592 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

K-Acetyltransferase 5 (KAT5), ELISA Kit - MBS9399437 from MyBioSource Category ELISA Kit

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