TREM1

Gene Symbol	TREM1
Entrez Gene	54210
Alt Symbol	CD354, TREM-1
Species	Human
Gene Type	protein-coding
Description	triggering receptor expressed on myeloid cells 1
Other Description	triggering receptor expressed on monocytes 1|triggering-receptor TREM1
Swissprots	B4DWG2 Q5T2C9 K7EJW1 Q9NP99 Q86YU1 Q53FL8
Accessions	ABB01010 CAJ78384 EAX04043 EAX04044 Q9NP99 AF196329 AAF71694 AF287008 AAF90197 AK130673 AK223264 BAD96984 AK292162 BAF84851 AK301519 BAG63024 AK313104 BAG35927 AY074783 AAL74018 BC017773 AAH17773 DA362458 DA938757 DQ892009 ABM82935 DQ895198 ABM86124 XM_006715117 XP_006715180 XM_011514696 XP_011512998 XM_011514697 XP_011512999 NM_001242589 NP_001229518 NM_001242590 NP_001229519 NM_018643 NP_061113
Function	Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. {ECO:0000269|PubMed:10799849, ECO:0000269|PubMed:11323674}.
Subcellular Location	Isoform 1: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes. {ECO:0000269|PubMed:10799849, ECO:0000269|PubMed:11922939}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TREM1-Over-expression-Lysate - LY15971a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

TREM1 293T Cell Transient Overexpression Lysate(Denatured) - H00054210-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

TREM1 293 Cell Lysate - 402352 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

TREM-1 Overexpression Lysate (Denatured) - H00054210-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

TREM-1 Overexpression Lysate (Native) - NBL1-17264 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TREM1 Over-expression Lysate Product - GWB-981072 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human TREM1 HEK293 Cell Lysate (WB positive control) - 10511-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human TREM1 HEK293 Cell Lysate (WB positive control) - 10511-H03HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human TREM1 Human Cells Transfected Lysate (positive control) (denatured) - orb179352 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

TREM-1 Overexpression Lysate (Denatured) - H00054210-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Human TREM1 Human Cells Transfected Lysate (positive control) (denatured) - orb173030 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human TREM1 Knockdown Stable Cell Line - CSC-DC016548 from Creative biogene Category Cell Line Species Human

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